Protein Information

Name interleukin 10
Synonyms B TCGF; B cell derived T cell growth factor; CSIF; Cytokine synthesis inhibitory factor; IL 10; IL10; IL10A; Interleukin 10…

Compound Information

Name formaldehyde
CAS formaldehyde

Reference List

PubMed Abstract RScore(About this table)
18849615 Sasaki Y, Ohtani T, Ito Y, Mizuashi M, Nakagawa S, Furukawa T, Horii A, Aiba S: Molecular events in human T cells treated with diesel exhaust particles or formaldehyde that underlie their diminished interferon-gamma and interleukin-10 production. Int Arch Allergy Immunol. 2009;148(3):239-50. Epub 2008 Oct 10.
32(0,1,1,2) Details
19422874 De Jong WH, Arts JH, De Klerk A, Schijf MA, Ezendam J, Kuper CF, Van Loveren H: Contact and respiratory sensitizers can be identified by cytokine profiles following inhalation exposure. Toxicology. 2009 Jul 10;261(3):103-11. Epub 2009 May 5.

After inhalation exposure the respiratory sensitizers induced more interleukin-4 (IL-4) and interleukin (IL-10) compared to the contact sensitizers, whereas the contact sensitizers, except formaldehyde, induced relatively more interferon-gamma (IFN-gamma) production.
31(0,1,1,1) Details
18033311 Zhou Z, Peng X, Hao S, Fink DJ, Mata M: HSV-mediated transfer of interleukin-10 reduces inflammatory pain through modulation of membrane tumor necrosis factor alpha in spinal cord microglia. Gene Ther. 2008 Feb;15(3):183-90. Epub 2007 Nov 22.

6(0,0,0,6) Details
17969629 Dehlink E, Domig KJ, Loibichler C, Kampl E, Eiwegger T, Georgopoulos A, Kneifel W, Urbanek R, Szepfalusi Z: Heat- and formalin-inactivated probiotic bacteria induce comparable cytokine patterns in intestinal epithelial cell-leucocyte cocultures. J Food Prot. 2007 Oct;70(10):2417-21.


To further investigate the influence of inactivation treatment on cytokine production, three probiotic strains were evaluated-live, heat-inactivated, and formalin-inactivated strains-for their impact on interleukin (IL) 6, IL-8, and IL-10 production in Caco-2-leucocyte cocultures.
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17870246 Menetski J, Mistry S, Lu M, Mudgett JS, Ransohoff RM, Demartino JA, Macintyre DE, Abbadie C: Mice overexpressing chemokine ligand 2 (CCL2) in astrocytes display enhanced nociceptive responses. Neuroscience. 2007 Nov 9;149(3):706-14. Epub 2007 Aug 14.


Consequently, proinflammatory cytokine mRNA expression (IL-1beta, IL-6, and TNFalpha) levels were greater in skin, dorsal root ganglia (DRG), and spinal cord, whereas the anti-inflammatory cytokine (IL-10) level was lower in skin and DRG in CCL2 overexpressing mice than in control mice.
1(0,0,0,1) Details
17570926 Gisch K, Gehrke N, Bros M, Priesmeyer C, Knop J, Reske-Kunz AB, Sudowe S: Formalin-fixed Staphylococcus aureus particles prevent allergic sensitization in a murine model of type I allergy. Int Arch Allergy Immunol. 2007;144(3):183-96. Epub 2007 Jun 15.


Culture of bone marrow-derived dendritic cells with Staphylococcus particles induced IL-12p35 and p40 mRNA expression as well as secretion of IL-12p70, and increased production of IL-10 mRNA and protein.
1(0,0,0,1) Details