Protein Information

Name C10
Synonyms C10; C10 protein; GRCC10; Gene rich cluster C10; Putative C10 protein; C10 proteins; Gene rich cluster C10s; Putative C10 proteins

Compound Information

Name benzalkonium chloride
CAS quaternary ammonium compounds, alkylbenzyldimethyl, chlorides

Reference List

PubMed Abstract RScore(About this table)
18057726 Nakamura T, Yamada M, Teshima M, Nakashima M, To H, Ichikawa N, Sasaki H: Electrophysiological characterization of tight junctional pathway of rabbit cornea treated with ophthalmic ingredients. Biol Pharm Bull. 2007 Dec;30(12):2360-4.

The ophthalmic ingredients used in the present study were benzalkonium chloride (BK; 0.002%, 0.01%, 0.05%), ethylenediaminetetraacetic acid (EDTA; 0.5%), capric acid (C10; 0.25%), saponin (SP; 0.1%), taurocholic acid (TA; 1.0%) and sodium dodecyl sulfate (SDS; 0.01%).
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3998184 Euerby MR: High performance liquid chromatography of benzalkonium chlorides--variation in commercial preparations. J Clin Hosp Pharm. 1985 Mar;10(1):73-7.

High performance liquid chromatography (HPLC) has been used to identify and determine the various alkyl benzyldimethylammonium chloride homologues (C10 to C16) present in commercial benzalkonium chloride preparations.
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9659709 Kawakami S, Callicott RH, Zhang N: Trace analysis of benzalkonium chloride on skin by flow injection ionspray mass spectrometry-mass spectrometry. Analyst. 1998 Mar;123(3):489-91.

Quantification was carried out using an external standard based on peak area summation of each benzalkonium ion (C8, C10, C12, C14, C16 and C18) in the mass spectra.
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17011092 Martinez-Carballo E, Gonzalez-Barreiro C, Sitka A, Kreuzinger N, Scharf S, Gans O: Determination of selected quaternary ammonium compounds by liquid chromatography with mass spectrometry. Environ Pollut. 2007 Mar;146(2):543-7. Epub 2006 Sep 28.

In general sediments were especially contaminated by C12 chain benzalkonium chloride (BAC-C12) as well as by the long C-chain dialkyldimethylammonium chloride (DDAC-C18) with a maximum concentration of 3.6 mg/kg and 2.1mg/kg, respectively.
Maxima of 27 mg/kg for DDAC-C10, 25 mg/kg for BAC-C12 and 23 mg/kg for BAC-C14 were determined for sludge samples.
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