| Name | HER2 |
|---|---|
| Synonyms | C erb B2; NEU; C erb B2/neu protein; C erbB 2; CD340 antigen; ERBB 2; ERBB2; ErbB 2 isoform a… |
| Name | formaldehyde |
|---|---|
| CAS | formaldehyde |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19204209 | Sauter G, Lee J, Bartlett JM, Slamon DJ, Press MF: Guidelines for human epidermal growth factor receptor 2 testing: biologic and methodologic considerations. J Clin Oncol. 2009 Mar 10;27(8):1323-33. Epub 2009 Feb 9. These considerations are clearly important in clinical practice because HER2 amplification is directly linked to protein expression levels in breast cancer. |
1(0,0,0,1) | Details |
| 17525107 | Mullins M, Perreard L, Quackenbush JF, Gauthier N, Bayer S, Ellis M, Parker J, Perou CM, Szabo A, Bernard PS: Agreement in breast cancer classification between microarray and quantitative reverse transcription PCR from fresh-frozen and formalin-fixed, paraffin-embedded tissues. Clin Chem. 2007 Jul;53(7):1273-9. Epub 2007 May 24. METHODS: We used microarray data from 124 breast samples as a training set for classifying tumors into 4 previously defined molecular subtypes: Luminal, HER2 (+)/ER (-), basal-like, and normal-like. |
1(0,0,0,1) | Details |
| 17957336 | Mullan PB, Millikan RC: Molecular subtyping of breast cancer: opportunities for new therapeutic approaches. Cell Mol Life Sci. 2007 Dec;64(24):3219-32. Prominent among the new subtypes is 'basal-like' breast cancer, one of the 'intrinsic' subtypes defined by negativity for the and HER2/neu receptors and positivity for cytokeratins-5/6. |
1(0,0,0,1) | Details |
| 19775342 | Lesnikova I, Lidang M, Hamilton-Dutoit S, Koch J: HER2/neu (c-erbB-2) gene amplification and protein expression are rare in uterine cervical neoplasia: a tissue microarray study of 814 archival specimens. APMIS. 2009 Oct;117(10):737-45. We examined tissue microarrays (TMAs) constructed from 814 formaldehyde-fixed paraffin-embedded archival specimens of cervical intraepithelial neoplasia (CIN) 1 (n = 262), CIN2 (n = 230), CIN3 (n = 186) and invasive carcinoma (n = 136), for HER2/neu protein expression by immunohistochemistry (IHC) and for HER2/neu gene amplification by chromogenic in situ hybridization (CISH). |
12(0,0,1,7) | Details |
| 18251579 | Vani K, Sompuram SR, Fitzgibbons P, Bogen SA: National HER2 proficiency test results using standardized quantitative controls: characterization of laboratory failures. Arch Pathol Lab Med. 2008 Feb;132(2):211-6. |
7(0,0,0,7) | Details |
| 19225135 | Iverson AA, Gillett C, Cane P, Santini CD, Vess TM, Kam-Morgan L, Wang A, Eisenberg M, Rowland CM, Hessling JJ, Broder SE, Sninsky JJ, Tutt A, Anderson S, Chang SY: A single-tube quantitative assay for mRNA levels of hormonal and growth factor receptors in breast cancer specimens. J Mol Diagn. 2009 Mar;11(2):117-30. Recently, growth factor receptor HER2/neu (ERBB2) status has made it possible to provide another form of targeted therapy linked to the overexpression of this protein. |
5(0,0,0,5) | Details |
| 17471153 | Kanemitsu S, Hisaoka M, Shimajiri S, Matsuyama A, Hashimoto H: Molecular detection of SS18-SSX fusion gene transcripts by cRNA in situ hybridization in synovial sarcoma using formalin-fixed, paraffin-embedded tumor tissue specimens. Diagn Mol Pathol. 2007 Mar;16(1):9-17. The localizations of signals were compared with the immunohistochemical expressions of epithelial or neuroectodermal markers and those of cell adhesion including cytokeratins (CAM5.2, AE1/AE3, CK7), epithelial membrane antigen, E-cadherin, beta-catenin, c-erbB-2 (HER2/neu), CD56, and claudin-1. |
2(0,0,0,2) | Details |
| 19617290 | Bohmann K, Hennig G, Rogel U, Poremba C, Mueller BM, Fritz P, Stoerkel S, Schaefer KL: RNA extraction from archival formalin-fixed paraffin-embedded tissue: a comparison of manual, semiautomated, and fully automated purification methods. Clin Chem. 2009 Sep;55(9):1719-27. Epub 2009 Jul 17. RNA from 360 sections (90 sections per extraction method) of 30 FFPE tumor blocks up to 20 years of age was purified and analyzed by quantitative reverse-transcription PCR for ESR1 (estrogen receptor 1), PGR (progesterone receptor), ERBB2 [v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)], and RPL37A (ribosomal protein L37a). |
1(0,0,0,1) | Details |