Protein Information

Name bcl 2
Synonyms Apoptosis regulator Bcl 2; B cell CLL/lymphoma 2; B cell lymphoma protein 2 alpha; B cell lymphoma protein 2 alpha isoform; BCL2; Bcl 2; B cell CLL/lymphoma 2s; B cell lymphoma protein 2 alphas…

Compound Information

Name formaldehyde
CAS formaldehyde

Reference List

PubMed Abstract RScore(About this table)
19112572 Hassa H, Tanir HM, Tekin B, Artan S, Dundar E, Kirilmaz SD, Sahin Mutlu F: Apoptosis patterns in eutopic and ectopic endometrium, adhesions and normal-looking peritoneum from women with or without endometriosis. Arch Gynecol Obstet. 2009 Aug;280(2):195-9. Epub 2008 Dec 27.

Normal-looking peritoneum, peritoneal implants and adhesions were sampled and fixed in formaldehyde for immunohistochemical staining with Bcl-2 and Bax.
6(0,0,1,1) Details
19737541 Ugarenko M, Nudelman A, Rephaeli A, Kimura KI, Phillips DR, Cutts SM: ABT-737 overcomes Bcl-2 mediated resistance to doxorubicin-DNA adducts. Biochem Pharmacol. 2009 Sep 6.

Doxorubicin is an anthracycline anticancer agent that functions primarily by inhibiting topoisomerase II, but also forms covalent DNA adducts depending on the cellular availability of formaldehyde.
5(0,0,0,5) Details
18822355 Jalalvand E, Javan M, Haeri-Rohani A, Ahmadiani A: Stress- and non-stress-mediated mechanisms are involved in pain-induced apoptosis in hippocampus and dorsal lumbar spinal cord in rats. Neuroscience. 2008 Nov 19;157(2):446-52. Epub 2008 Sep 4.


Following exposure to repeated injections of 5% formalin, we detected Bax, Bcl-2, pro-caspase and activated caspase-3 proteins using immunoblotting.
2(0,0,0,2) Details
19425073 Kaneko T, Okiji T, Kaneko R, Suda H, Nor JE: Gene expression analysis of immunostained endothelial cells isolated from formaldehyde-fixated paraffin embedded tumors using laser capture microdissection-A technical report. Microsc Res Tech. 2009 May 7;72(12):908-912.

The expression of Bcl-2 in the endothelial cells was evaluated by RT-PCR and by real time PCR.
1(0,0,0,1) Details
19332347 Szilagyi G, Simon L, Wappler E, Magyar K, Nagy Z: (-) Deprenyl-N-oxide, a (-) deprenyl metabolite, is cytoprotective after hypoxic injury in PC12 cells, or after transient brain ischemia in gerbils. J Neurol Sci. 2009 Aug 15;283(1-2):182-6. Epub 2009 Mar 29.

Apoptotic neurons were counted on formaldehyde fixed gerbil brain slices after TUNEL and caspase-3 immune-staining - NIKON/BIORAD confocal microscopy was used for the quantitative analysis.
Augmented Bcl-2 protein expression was documented as the responsible factor of this effect.
1(0,0,0,1) Details