| 18506586 |
Tarasenko N, Nudelman A, Tarasenko I, Entin-Meer M, Hass-Kogan D, Inbal A, Rephaeli A: Histone deacetylase inhibitors: the anticancer, antimetastatic and antiangiogenic activities of AN-7 are superior to those of the clinically tested AN-9 (Pivanex). Clin Exp Metastasis. 2008;25(7):703-16. Epub 2008 May 28.
Histone deacetylase inhibitory prodrugs that are metabolized to butyric acid and formaldehyde possess antineoplastic properties and low toxicity. |
32(0,1,1,2) |
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| 18030472 |
Levovich I, Nudelman A, Berkovitch G, Swift LP, Cutts SM, Phillips DR, Rephaeli A: Formaldehyde-releasing prodrugs specifically affect cancer cells by depletion of intracellular glutathione and augmentation of reactive oxygen species. Cancer Chemother Pharmacol. 2008 Aug;62(3):471-82. Epub 2007 Nov 21.
Histone deacetylase inhibitory prodrugs that are metabolized to carboxylic acid (s) and aldehyde (s) possess antineoplastic properties. |
1(0,0,0,1) |
Details |