Name | P gp |
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Synonyms | ABC20; MDR1; ABCB 1; ABCB1; ATP binding cassette sub family B member 1; CD243; CD243 antigen; CLCS… |
Name | formaldehyde |
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CAS | formaldehyde |
PubMed | Abstract | RScore(About this table) | |
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17822280 | Cutts SM, Nudelman A, Pillay V, Spencer DM, Levovich I, Rephaeli A, Phillips DR: Formaldehyde-releasing prodrugs in combination with adriamycin can overcome cellular drug resistance. Oncol Res. 2005;15(4):199-213. Combinations of Adriamycin with selected prodrugs that release one or two moles of formaldehyde partially overcame P-glycoprotein-mediated resistance in MES-SA/Dx5 cells. |
31(0,1,1,1) | Details |
17431124 | Cutts SM, Swift LP, Pillay V, Forrest RA, Nudelman A, Rephaeli A, Phillips DR: Activation of clinically used anthracyclines by the formaldehyde-releasing prodrug pivaloyloxymethyl Mol Cancer Ther. 2007 Apr;6(4):1450-9. To determine which anthracyclines would be useful in combination with formaldehyde-releasing prodrugs, a series of clinically relevant anthracyclines (doxorubicin, daunorubicin, idarubicin, and epirubicin) were examined for their capacity to form DNA adducts in MCF7 and MCF7/Dx (P-glycoprotein overexpressing) cells in the presence of the formaldehyde-releasing drug pivaloyloxymethyl (AN-9). |
6(0,0,1,1) | Details |
19499709 | Bogush TA, Dudko EA, Bogush EA, Baryshnikov AIu: [Parameters of specific antibody interaction with P-gp in T-cell leukemia Jurkat cells]. Antibiot Khimioter. 2009;54(1-2):3-9. Optimal condition of incubation with the antibodies was revealed--after the cell fixation in 4% formaldehyde. 2. |
1(0,0,0,1) | Details |