11087550 |
Nagahori H, Yoshino H, Tomigahara Y, Isobe N, Kaneko H, Nakatsuka I: Metabolism of furametpyr. 1. J Agric Food Chem. 2000 Nov;48(11):5754-9.
The major biotransformation reactions of furametpyr in rats were found to be (1) N-demethylation, (2) oxidation of the methyl group at C3 of the pyrazole ring, (3) oxidation of the methyl group at C1 of the 1,3-dihydroisobenzofuran ring, (4) hydroxylation at C3 of the 1,3-dihydroisobenzofuran ring, and (5) hydroxylation at C7 of the 1, 3-dihydroisobenzofuran ring. |
81(1,1,1,1) |
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