Protein Information

Name prion protein
Synonyms ASCR; PRIP; PRP; PRNP; Prion related protein; CD230; CD230 antigen; CJD…

Compound Information

Name TCA
CAS 2,2,2-trichloroacetic acid

Reference List

PubMed Abstract RScore(About this table)
19583442 Mangels C, Frank AO, Ziegler J, Klingenstein R, Schweimer K, Willbold D, Korth C, Rosch P, Schwarzinger S: Binding of TCA to the prion protein: mechanism, implication for therapy, and application as probe for complex formation of bio-macromolecules. J Biomol Struct Dyn. 2009 Oct;27(2):163-70.

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15307294 Zaborowski A: [Creutzfeldt-Jakob disease and other human transmissible spongiform encephalopathies. Psychiatr Pol. 2004 Mar-Apr;38(2):297-309.


The only certain diagnostic marker for TSE is PrP (Sc), prion protein, presently believed to be a direct cause for all TSEs (TCAs).
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15307293 Zaborowski A: [Creutzfeldt-Jakob disease and other human transmissible spongiform encephalopathies. Psychiatr Pol. 2004 Mar-Apr;38(2):283-96.


The only certain diagnostic marker for TSE is the presence of PrP (Sc), the prion protein, which is presently believed to be a direct cause for all transmissible cerebral amyloidoses (TCA).
1(0,0,0,1) Details