Name | SP4 |
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Synonyms | HF1B; SP4; SPR 1; Sp4 transcription factor; Transcription factor Sp4; Sp4 transcription factors; Transcription factor Sp4s |
Name | benzalkonium chloride |
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CAS | quaternary ammonium compounds, alkylbenzyldimethyl, chlorides |
PubMed | Abstract | RScore(About this table) | |
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2444699 | Repke H, Piotrowski W, Bienert M, Foreman JC: mast cells. J Pharmacol Exp Ther. 1987 Oct;243(1):317-21. Unlike dodecylamine itself, SP1-4C12 induced noncytolytic release which was inhibited by benzalkonium chloride and by the substance P antagonist [D-Pro4,D-Trp7,9,10] SP4-11. |
release induced by Arg-Pro- -Pro (CH2) 11CH3 from rat peritoneal 81(1,1,1,1) | Details |
2417614 | Piotrowski W, Foreman JC: Some effects of calcitonin gene-related peptide in human skin and on release. Br J Dermatol. 1986 Jan;114(1):37-46. The substance P analogue, [D-Pro4, D-Trp7,9,10] SP4-11 10 microM, and benzalkonium chloride 10 microM inhibited release from rat mast cells stimulated by either CGRP or substance P. |
31(0,1,1,1) | Details |
2419771 | Piotrowski W, Foreman JC: On the actions of substance P, somatostatin, and vasoactive intestinal polypeptide on rat peritoneal mast cells and in human skin. Naunyn Schmiedebergs Arch Pharmacol. 1985 Dec;331(4):364-8. The release of induced by these neuropeptides was inhibited by preincubation of the cells with the SP analogue [D-Pro4,D-Trp7,9,10]-SP4-11 (SP-A) (10 microM), and also by benzalkonium chloride (10 microM). |
31(0,1,1,1) | Details |
2440265 | Piotrowski W, Mead M, Foreman JC: Action of the SP2-11 and SP3-11 fragments of substance P on rat peritoneal mast cells. Agents Actions. 1987 Apr;20(3-4):178-80. The substance P antagonist [D-Pro4, D-Trp7,9,10] SP4-11 was equally effective at antagonizing the releasing action of SP1-11, SP2-11 and SP3-11. Benzalkonium chloride was found to be a competitive antagonist of SP and SP3-11: the dissociation constants for the benzalkonium chloride-receptor interaction being about the same when either SP1-11 or SP3-11 was used as the agonist. |
1(0,0,0,1) | Details |