Protein Information

Name monoamine oxidase
Synonyms Adrenalin oxidase; Amine oxidase; Amine oxidase [flavin containing] B; MAO B; MAOB; Monoamine oxidase; Monoamine oxidase B; Monoamine oxidase type B…

Compound Information

Name dichlorvos
CAS 2,2-dichloroethenyl dimethyl phosphate

Reference List

PubMed Abstract RScore(About this table)
12018584 Nag M, Nandy N: Serotonin and benzylamine oxidation by type A and type B MAO of rat brain in presence of organophosphate pesticides. Indian J Exp Biol. 2001 Aug;39(8):802-6.

Organophosphate (OP) pesticides, monocrotophos (MCP), dichlorvos (DDVP) and phosphamidon significantly inhibit both MAO-A and MAO-B activities in rat brain mitochondria.
82(1,1,1,2) Details
6443171 Maslinska D: Brain monoamine oxidase in suckling rabbits treated with organophosphorus compound. Acta Physiol Pol. 1984 Mar-Apr;35(2):137-40.

In 16-day-old rabbits treated with dichlorvos 8 mg/kg per os the activity of monoamine oxidase A form (MAO A) in brain was studied.
1(0,0,0,1) Details
12186780 Choudhary S, Raheja G, Gupta V, Gill KD: Possible involvement of dopaminergic neurotransmitter system in dichlorvos induced delayed neurotoxicity. J Biochem Mol Biol Biophys. 2002 Feb;6(1):29-36.

This increase was accompanied with a concomitant decrease in the activity of the major degradative enzyme, monoamine oxidase.
1(0,0,0,1) Details
3446596 Nag M, Nandi N: Inhibition of monoamine oxidase activity by some organophosphate pesticides. Indian J Exp Biol. 1987 Aug;25(8):567-8.

1(0,0,0,1) Details
20026515 Dwivedi N, Bhutia YD, Kumar V, Yadav P, Kushwaha P, Swarnkar H, Flora SJ: Effects of combined exposure to dichlorvos and monocrotophos on blood and brain biochemical variables in rats. Hum Exp Toxicol. 2010 Feb;29(2):121-9. Epub 2009 Dec 21.

We studied the effect of concomitant exposure to DDVP and MC on selected biochemical variables suggestive of liver damage, changes in whole brain biogenic amines levels, acetylcholinesterase (AchE) and monoamine oxidase (MAO) activities in rats.
1(0,0,0,1) Details