| Name | glutathione S transferase |
|---|---|
| Synonyms | GST class alpha 2; Gst2; GST class alpha; GST class alpha member 2; GST gamma; GSTA 2; GSTA2; GSTA2 2… |
| Name | cycloheximide |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15837795 | Beischlag TV, Perdew GH: ER alpha-AHR-ARNT protein-protein interactions mediate -dependent transrepression of dioxin-inducible gene transcription. J Biol Chem. 2005 Jun 3;280(22):21607-11. Epub 2005 Apr 18. Both AHR and ARNT were capable of interacting directly with ER alpha, as ascertained by glutathione S-transferase pull-down. 17Beta- repressed TCDD-activated Cyp1a1 and Cyp1b1 gene transcription in MCF-7 cells in the presence of cycloheximide, as determined by reverse transcription/real-time PCR. |
81(1,1,1,1) | Details |
| 15993699 | Fatima RA, Ahmad M: Certain antioxidant enzymes of Allium cepa as biomarkers for the detection of toxic heavy metals in wastewater. Sci Total Environ. 2005 Jun 15;346(1-3):256-73. In the presence of cycloheximide, all the enzymes returned to the levels of untreated controls while chloramphenicol did not have any effect on the test enzymes, thereby suggesting de novo protein synthesis of the test antioxidant enzymes in the cytosolic compartment of the cell as a result of exposure to the heavy metals. The utility of antioxidant enzymes, viz glutathione-S-transferase (GST), glutathione reductase (GR), superoxide dismutase (SOD), catalase (CAT), peroxidase (APX), peroxidase (GPX), monodehydroascorbate reductase (MDHAR) and reductase (DHAR), as biomarkers of heavy metal pollution in water was investigated using the Allium cepa (onion) system. |
1(0,0,0,1) | Details |
| 16243960 | Korashy HM, El-Kadi AO: Transcriptional regulation of the NAD (P) H:quinone oxidoreductase 1 and glutathione S-transferase ya genes by mercury, lead, and Drug Metab Dispos. 2006 Jan;34(1):152-65. Epub 2005 Oct 21. The protein synthesis inhibitor cycloheximide significantly inhibited metal-mediated induction of Nqo1 and Gst ya mRNAs, which coincided with a decrease in the nuclear factor erythroid 2-related factor 2 (Nrf2) protein expression, implying the requirement of Nrf2 protein synthesis for the induction of these genes. |
2(0,0,0,2) | Details |
| 18618763 | Wu MC, Lu KH: Juvenile hormone induction of glutathione S-transferase activity in the larval fat body of the common cutworm, Spodoptera litura (Lepidoptera: Noctuidae). Arch Insect Biochem Physiol. 2008 Aug;68(4):232-40. The suppressive effects of alpha-amanitin and cycloheximide suggest that JHA induction of GST activity in these cutworm larvae presumably occurred at the gene transcription level. |
1(0,0,0,1) | Details |
| 18650263 | Liu T, Huang Y, Likhotvorik RI, Keshvara L, Hoyt DG: Protein Never in Mitosis Gene A Interacting-1 (PIN1) regulates degradation of inducible synthase in endothelial cells. Am J Physiol Cell Physiol. 2008 Sep;295(3):C819-27. Epub 2008 Jul 23. Consistent with posttranscriptional action, knockdown of PIN1 increased the stability of iNOS protein in cycloheximide-treated cells. |
0(0,0,0,0) | Details |