| Name | ATPases |
|---|---|
| Synonyms | (NA+ + K+)ATPase; ATP1A1; ATPase; ATPase Na+/K+ transporting alpha 1 polypeptide; Na (+) K (+) ATPase; Na (+),K (+) ATPase; Na + K + ATPase; Na K + ATPase… |
| Name | cycloheximide |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15713908 | Banday AA, Siddiqui AH, Menezes MM, Hussain T: Insulin treatment enhances AT1 receptor function in OK cells. Am J Physiol Renal Physiol. 2005 Jun;288(6):F1213-9. Epub 2005 Feb 15. The present study investigates the effect of insulin treatment on AT1 receptor expression and ANG II-induced stimulation of Na/H exchanger (NHE) and Na-K-ATPase (NKA) in opossum kidney (OK) cells, a proximal tubule cell line. The whole cell lysate and membrane showed similar insulin-induced increase in the AT1 receptor protein expression, which was blocked by (100 nM), a kinase inhibitor, and cycloheximide (1.5 microg/ml), a protein synthesis inhibitor. |
1(0,0,0,1) | Details |
| 19401877 | Hatou S, Yamada M, Mochizuki H, Shiraishi A, Joko T, Nishida T: The effects of dexamethasone on the Na,K-ATPase activity and pump function of corneal endothelial cells. Curr Eye Res. 2009 May;34(5):347-54. These effects of dexamethasone were blocked by cycloheximide, a protein synthesis inhibitor. |
10(0,0,0,10) | Details |
| 20199105 | Tokhtaeva E, Munson K, Sachs G, Vagin O: N-Glycan-Dependent Quality Control of the Na,K-ATPase beta (2) Subunit. Biochemistry. 2010 Mar 17. Calnexin binding persists for several hours after translation is stopped with cycloheximide, suggesting that the beta (2) subunit undergoes repeated post-translational calnexin-assisted folding attempts. |
4(0,0,0,4) | Details |
| 18344484 | Zuo J, Vergara S, Kohno S, Holliday LS: Biochemical and functional characterization of the actin-binding activity of the B subunit of yeast vacuolar H+-ATPase. J Exp Biol. 2008 Apr;211(Pt 7):1102-8. The B subunits of V-ATPases from mammals and tobacco hornworm have been shown to bind actin filaments. Screening null yeast or null yeast transformed with wild-type or mutant B subunits with sub-lethal doses of various drugs revealed that yeast containing the mutant B subunits were more sensitive to cycloheximide and wortmannin than those transformed with wild-type B subunits. |
2(0,0,0,2) | Details |
| 15695513 | Vagin O, Turdikulova S, Yakubov I, Sachs G: Use of the H,K-ATPase beta subunit to identify multiple sorting pathways for plasma membrane delivery in polarized cells. J Biol Chem. 2005 Apr 15;280(15):14741-54. Epub 2005 Feb 4. Hence, co-sorting of the H,K-ATPase beta subunit with the Na,K-ATPase alpha (1) subunit to the basolateral membrane in MDCK cells may determine the differential distribution of the beta subunit in these two cell types. |
1(0,0,0,1) | Details |
| 19877184 | Haurie V, Menard L, Nicou A, Touriol C, Metzler P, Fernandez J, Taras D, Lestienne P, Balabaud C, Bioulac-Sage P, Prats H, Zucman-Rossi J, Rosenbaum J: triphosphatase pontin is overexpressed in hepatocellular carcinoma and coregulated with reptin through a new posttranslational mechanism. Hepatology. 2009 Dec;50(6):1871-83. This restoration was not observed when cells were also treated with cycloheximide, thus confirming that proteasomal degradation in this setting was restricted to newly synthesized Pontin. Reptin and Pontin are related ATPases associated with stoichiometric amounts in several complexes involved in chromatin remodeling, transcriptional regulation, and telomerase activity. |
1(0,0,0,1) | Details |
| 17310067 | Cottrell GS, Padilla B, Pikios S, Roosterman D, Steinhoff M, Grady EF, Bunnett NW: Post-endocytic sorting of calcitonin receptor-like receptor and receptor activity-modifying protein 1. J Biol Chem. 2007 Apr 20;282(16):12260-71. Epub 2007 Feb 19. Cycloheximide did not affect resensitization, but bafilomycin A (1), an inhibitor of vacuolar H (+)-ATPases, abolished resensitization. |
0(0,0,0,0) | Details |