Name | Aa nat |
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Synonyms | AA NAT; AANAT; AANAT protein; Aralkylamine N acetyltransferase; Arylalkylamine N acetyltransferase; SNAT; Serotonin N acetyltransferase; Serotonin acetylase… |
Name | cycloheximide |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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16099857 | Terriff DL, Chik CL, Price DM, Ho AK: Proteasomal proteolysis in the adrenergic induction of arylalkylamine-N-acetyltransferase in rat pinealocytes. Endocrinology. 2005 Nov;146(11):4795-803. Epub 2005 Aug 11. This possibility was also supported by the finding that the inhibitory effect of c-lact on NE-induced aa-nat induction was markedly reduced by cycloheximide, a protein synthesis inhibitor. |
87(1,1,1,7) | Details |
17014691 | Fernandes PA, Cecon E, Markus RP, Ferreira ZS: Effect of TNF-alpha on the pineal gland: basis for a 'feedback' of the immune response on circadian timing. J Pineal Res. 2006 Nov;41(4):344-50. In fact, a protein (s) transcribed, later on, as shown by cycloheximide, was responsible for the reversal of the inhibition of Aa-nat transcription. |
synthetic pathway in the rat 84(1,1,1,4) | Details |
16887909 | Sinitskaya N, Salingre A, Klosen P, Revel FG, Pevet P, Simonneaux V: Differential expression of activator protein-1 proteins in the pineal gland of Syrian hamster and rat may explain species diversity in arylalkylamine N-acetyltransferase gene expression. Endocrinology. 2006 Nov;147(11):5052-60. Epub 2006 Aug 3. Indeed, early-night administration of a protein synthesis inhibitor (cycloheximide) markedly decreased AA-NAT mRNA levels in Syrian hamster. |
6(0,0,0,6) | Details |
19470703 | Kanyo R, Price DM, Chik CL, Ho AK: Salt-inducible kinase 1 in the rat pinealocyte: adrenergic regulation and role in arylalkylamine N-acetyltransferase gene transcription. Endocrinology. 2009 Sep;150(9):4221-30. Epub 2009 May 21. |
6(0,0,0,6) | Details |
16687308 | Simonneaux V, Sinitskaya N, Salingre A, Garidou ML, Pevet P: Rat and Syrian hamster: two models for the regulation of AANAT gene expression. Chronobiol Int. 2006;23(1-2):351-9. Interestingly, injection of the protein synthesis inhibitor cycloheximide before, but not after, the c-FOS/c-JUN peak markedly reduces Aanat mRNA levels. |
4(0,0,0,4) | Details |