| Name | TSP1 |
|---|---|
| Synonyms | CRISP 2; TSP 1; TSP1; CRISP2; Cysteine rich secretory protein 2; Cysteine rich secretory protein 2 precursor; GAPDL 5; GAPDL5… |
| Name | cycloheximide |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16723184 | Mattila MM, Tarkkonen KM, Seppanen JA, Ruohola JK, Valve EM, Harkonen PL: Androgen and fibroblast growth factor 8 (FGF8) downregulation of thrombospondin 1 (TSP1) in mouse breast cancer cells. Mol Cell Endocrinol. 2006 Jul 11;253(1-2):36-43. Epub 2006 May 24. Experiments with cycloheximide suggested that Te repression of TSP1 was dependent on de novo protein synthesis. |
14(0,0,1,9) | Details |
| 17955499 | Shi L, Liu S, Nikolic D, Wang S: High glucose levels upregulate upstream stimulatory factor 2 gene transcription in mesangial cells. J Cell Biochem. 2008 Apr 15;103(6):1952-61. Previously, we demonstrated that upstream stimulatory factor 2 (USF2) mediates high -induced thrombospondin1 (TSP1) gene expression and TGF-beta activity in glomerular mesangial cells and plays a role in diabetic renal complications. By using cycloheximide to block the de novo protein synthesis, similar rate of USF2 degradation was found under either normal or high conditions. |
1(0,0,0,1) | Details |