Protein Information

Name Vascular endothelial growth factor D
Synonyms FIGF; FOS induced growth factor; VEGF D; VEGFD; Vascular endothelial growth factor D; Vascular endothelial growth factor D precursor; c fos induced growth factor; c fos induced growth factor (vascular endothelial growth factor D)…

Compound Information

Name cycloheximide
CAS

Reference List

PubMed Abstract RScore(About this table)
16152591 Akahane M, Akahane T, Matheny SL, Shah A, Okajima E, Thorgeirsson UP: Vascular endothelial growth factor-D is a survival factor for human breast carcinoma cells. Int J Cancer. 2006 Feb 15;118(4):841-9.

The VEGF-D-expressing MCF-7 and MDA-MB-231 lines displayed resistance to apoptosis induced by hypoxia, staurosporin and cycloheximide.
14(0,0,1,9) Details
19301310 Goodyear SM, Kheyfets SB, Garcia FU, Stearns ME: Role of the VEGFR3/VEGFD receptor axis in TGFbeta1 activation of primary prostate cell lines. Prostate. 2009 Jun 15;69(9):982-90.

This event was not inhibited by 10 microM cycloheximide or puromycin, indicating transcription and protein synthesis were not required.
5(0,0,0,5) Details
18075819 Sena K, Sumner DR, Virdi AS: Modulation of VEGF expression in rat bone marrow stromal cells by GDF-5. Connect Tissue Res. 2007;48(6):324-31.


VEGF-D and its receptor VEGFR-3 showed peak expression at later time points.
2(0,0,0,2) Details