| Name | PDE4B |
|---|---|
| Synonyms | DPDE 4; DPDE4; Dunce like phosphodiesterase E4; PDE32; PDE4B; PDEIVB; cAMP specific 3 5 cyclic phosphodiesterase 4B; Dunce like phosphodiesterase E4s… |
| Name | cycloheximide |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16299053 | Busch CJ, Liu H, Graveline AR, Bloch KD: induces phosphodiesterase 4B expression in rat pulmonary artery smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2006 Apr;290(4):L747-L753. Epub 2005 Nov 18. The GSNO-induced increase in PDE4B mRNA levels was blocked by actinomycin D but augmented by cycloheximide. |
85(1,1,1,5) | Details |
| 18311187 | Campos-Toimil M, Keravis T, Orallo F, Takeda K, Lugnier C: Short-term or long-term treatments with a phosphodiesterase-4 (PDE4) inhibitor result in opposing agonist-induced Ca (2+) responses in endothelial cells. Br J Pharmacol. 2008 May;154(1):82-92. Epub 2008 Mar 3. All these effects were suppressed by cycloheximide. Long-term pre-treatment with rolipram or db-cAMP induced a significant increase in PDE4 activity and the expression of 74 kDa-PDE4A and 73 kDa-PDE4B was specifically enhanced. |
2(0,0,0,2) | Details |