Name | CCL1 |
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Synonyms | CCL 1; CCL1; I 309; I309; Inflammatory cytokine I 309; P500; SCYA 1; SCYA1… |
Name | cycloheximide |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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19302817 | N'Diaye M, Le Ferrec E, Kronenberg F, Dieplinger H, Le Vee M, Fardel O: TNFalpha- and NF-kappaB-dependent induction of the chemokine CCL1 in human macrophages exposed to the atherogenic lipoprotein (a). Life Sci. 2009 Mar 27;84(13-14):451-7. Epub 2009 Feb 2. KEY FINDINGS: Using the AhR antagonist alpha-napthtoflavone, the translational inhibitor cycloheximide and anti-tumor necrosis factor alpha (TNFalpha) neutralizing antibodies, we demonstrated that Lp (a)-mediated mRNA induction of CCL1 occurs in an AhR-independent manner and requires de novo protein synthesis of TNFalpha. |
90(1,1,1,10) | Details |
19699525 | Harashima A, Toraya T, Okochi A, Yamamoto M, Suzuki M, Otani T, Inoue T, Tsuji-Takayama K, Sugimoto A, Takeuchi M, Yamasaki F, Nakamura S, Kibata M: Interleukin-8 and RANTES are signature cytokines made by HOZOT, a new type of regulatory T cells. Mol Immunol. 2009 Oct;46(16):3310-9. Epub 2009 Aug 21. Interestingly, IL-8 mRNA was induced by cycloheximide treatment and RANTES showed reduced mRNA but increased protein expression by antibody stimulation. Twelve genes, including IL-2, IL-3, IL-4, IL-22, CCL1, and lymphotactin, were categorized as antibody stimulation-responsive but stromal cell-non-responsive. |
1(0,0,0,1) | Details |