Protein Information

Name Interleukin 5
Synonyms B cell differentiation factor 1; B cell differentiation factor I; EDF; Eosinophil differentiation factor; IL 5; IL5; Interleukin 5; Interleukin 5 precursor…

Compound Information

Name cycloheximide
CAS

Reference List

PubMed Abstract RScore(About this table)
15722640 Park CS, Choi EN, Kim JS, Choi YS, Rhim TY, Chang HS, Chung IY: Interferon-gamma inhibits in vitro mobilization of eosinophils by interleukin-5. Int Arch Allergy Immunol. 2005 Mar;136(3):295-302. Epub 2005 Feb 16.

We further analyzed the IFN-gamma effect, showing that pretreatment with IFN-gamma strongly suppressed IL-5-induced eosinophil shape change, and cycloheximide (CHX) abrogated the suppression by IFN-gamma, suggesting that new protein synthesis is required for the inhibitory effect by this cytokine.
34(0,1,1,4) Details