Name | calcineurin (protein family or complex) |
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Synonyms | Calcineurin; Calcineurins; Protein phosphatase 2B |
Name | cycloheximide |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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17324936 | Saeki M, Irie Y, Ni L, Itsuki Y, Terao Y, Kawabata S, Kamisaki Y: Calcineurin potentiates the activation of procaspase-3 by accelerating its proteolytic maturation. J Biol Chem. 2007 Apr 20;282(16):11786-94. Epub 2007 Feb 26. Overexpression of calcineurin B in HEK293 cells potentiated processing of caspase-3 and apoptosis triggered by tumor necrosis factor-alpha and cycloheximide treatment. |
36(0,1,1,6) | Details |
16458016 | Canellada A, Cano E, Sanchez-Ruiloba L, Zafra F, Redondo JM: mediated by the calcineurin/NFAT pathway. Mol Cell Neurosci. 2006 Apr;31(4):692-701. Epub 2006 Feb 2. |
-dependent expression of TNF-alpha in neural cells is 4(0,0,0,4) | Details |
16000155 | Kramer D, Caruso A, Nicoletti F, Genazzani AA: Somatostatin and the somatostatin receptor 2 are reciprocally controlled by calcineurin during cerebellar granule cell maturation. J Neurochem. 2005 Sep;94(5):1374-83. Epub 2005 Jul 5. |
4(0,0,0,4) | Details |
15837527 | Tenhunen O, Szokodi I, Ruskoaho H: Posttranscriptional activation of BNP gene expression in response to increased left ventricular wall stress: role of calcineurin and PKC. Regul Pept. 2005 Jun 30;128(3):187-96. In contrast, the protein synthesis inhibitor cycloheximide increased baseline BNP mRNA levels and abolished the load-induced activation of gene expression. Furthermore, we studied the effects of protein kinase C (PKC), calcineurin and protein phosphatase 2A (PP2A) inhibition to characterize the role of intracellular pathways in the stretch-induced gene expression in the left ventricle. |
2(0,0,0,2) | Details |
17166486 | Takadera T, Ohyashiki T: Caspase-dependent apoptosis induced by calcineurin inhibitors was prevented by glycogen synthase kinase-3 inhibitors in cultured rat cortical cells. Brain Res. 2007 Feb 16;1133(1):20-6. Epub 2006 Dec 12. Calcineurin is selectively enriched within neurons of the central nervous system. In addition, insulin growth factor-I (IGF-I) and cycloheximide completely blocked cell death. |
1(0,0,0,1) | Details |
19244510 | Li S, Zhang C, Takemori H, Zhou Y, Xiong ZQ: TORC1 regulates activity-dependent CREB-target gene transcription and dendritic growth of developing cortical neurons. J Neurosci. 2009 Feb 25;29(8):2334-43. Ca (2+) influx via voltage-gated channels induced TORC1 dephosphorylation and translocation into the nucleus in a calcineurin-dependent manner. |
1(0,0,0,1) | Details |