Protein Information

Name GLUT 2
Synonyms GLUT 2; GLUT2; Glucose transporter 2; SLC2A2; Glucose transporter 2s

Compound Information

Name cycloheximide
CAS

Reference List

PubMed Abstract RScore(About this table)
19006119 Suh HN, Lee YJ, Han HJ: Interleukin-6 promotes 2-deoxyglucose uptake through p44/42 MAPKs activation via Ca2+/PKC and EGF receptor in primary cultured chicken hepatocytes. J Cell Physiol. 2009 Mar;218(3):643-52.

Indeed, IL-6 increased GLUT-2 mRNA and protein expression as well as 2-DG uptake, which were blocked by actinomycin D (AD, transcription inhibitor) and cycloheximide (CHX, translation inhibitor).
34(0,1,1,4) Details
19540219 Fu Z, Liu D: Long-term exposure to genistein improves insulin secretory function of pancreatic beta-cells. Eur J Pharmacol. 2009 Aug 15;616(1-3):321-7. Epub 2009 Jun 18.


The enhanced insulin secretion by genistein was associated with elevated intracellular Ca (2+) concentration and dependent on protein kinase A and new protein synthesis as this effect was completely blocked by N-[2-(p-Bromocinnamylamino) ethyl]-5-isoquinolinesulfonamide or cycloheximide.
0(0,0,0,0) Details