| Name | hTERT |
|---|---|
| Synonyms | ABG deleted variant of telomerase reverse transcriptase; EST 2; EST2; HEST 2; HEST2; TCS 1; TCS1; TERT… |
| Name | cycloheximide |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15791453 | Murakami J, Asaumi J, Kawai N, Tsujigiwa H, Yanagi Y, Nagatsuka H, Inoue T, Kokeguchi S, Kawasaki S, Kuroda M, Tanaka N, Matsubara N, Kishi K: Effects of histone deacetylase inhibitor FR901228 on the expression level of telomerase reverse transcriptase in oral cancer. Cancer Chemother Pharmacol. 2005 Jul;56(1):22-8. Epub 2005 Mar 25. Moreover, cotreatment of protein synthesis inhibitor cycloheximide (CHX) resulted in the induction of hTERT transcription by FR901228. |
37(0,1,1,7) | Details |
| 15516693 | Wang S, Zhu J: The hTERT gene is embedded in a nuclease-resistant chromatin domain. J Biol Chem. 2004 Dec 31;279(53):55401-10. Epub 2004 Oct 29. In contrast, the inhibition of protein synthesis by cycloheximide induced transcription from both the hTERT and Xtrp2 genes, indicating that histone deacetylases and labile factors coordinate to silence this chromosomal region. |
37(0,1,1,7) | Details |
| 16369022 | Edwards AM, Grossman TJ, Rudney JD: Fusobacterium nucleatum transports noninvasive Streptococcus cristatus into human epithelial cells. Infect Immun. 2006 Jan;74(1):654-62. Similar decreases were obtained when epithelial cells were pretreated with cytochalasin D, staurosporine, or cycloheximide. Coincubation of KB or TERT-2 epithelial cells with equal numbers of F. nucleatum and S. cristatus bacteria led to significantly increased numbers of adherent and internalized streptococci. |
1(0,0,0,1) | Details |
| 19301310 | Goodyear SM, Kheyfets SB, Garcia FU, Stearns ME: Role of the VEGFR3/VEGFD receptor axis in TGFbeta1 activation of primary prostate cell lines. Prostate. 2009 Jun 15;69(9):982-90. RESULTS: hTERT immortalized IBC-10a cells normally grew as confluent "cobblestoned" monolayers, but treatment with TGFbeta1 (10 ng/ml for 2-6 hr) dissociated the cell-cell junctions and induced VEGFR3 translocation to the cell surface. This event was not inhibited by 10 microM cycloheximide or puromycin, indicating transcription and protein synthesis were not required. |
1(0,0,0,1) | Details |