Name | ARNT |
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Synonyms | AAAP6077; TANGO; ARNT; C219 reactive peptide; MIA 3; MIA3; UNQ6077; UNQ6077 protein… |
Name | cycloheximide |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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15837795 | Beischlag TV, Perdew GH: ER alpha-AHR-ARNT protein-protein interactions mediate -dependent transrepression of dioxin-inducible gene transcription. J Biol Chem. 2005 Jun 3;280(22):21607-11. Epub 2005 Apr 18. Both AHR and ARNT were capable of interacting directly with ER alpha, as ascertained by glutathione S-transferase pull-down. 17Beta- repressed TCDD-activated Cyp1a1 and Cyp1b1 gene transcription in MCF-7 cells in the presence of cycloheximide, as determined by reverse transcription/real-time PCR. |
33(0,1,1,3) | Details |
16226227 | Pollenz RS, Popat J, Dougherty EJ: Role of the carboxy-terminal transactivation domain and active transcription in the ligand-induced and ligand-independent degradation of the mouse Ahb-1 receptor. Biochem Pharmacol. 2005 Nov 25;70(11):1623-33. Epub 2005 Oct 13. However, AD inhibited TCDD-induced degradation when ARNT expression was restored. To assess the importance of transactivation domains (TAD), DNA binding and transcription on the degradation of the AH receptor (AHR), Hepa-1 cells were pre-treated with actinomycin D (AD) or cycloheximide (CHX) and exposed to 2,3,7,8 tetrachlorodibenzo-p-dioxin (TCDD). |
1(0,0,0,1) | Details |