Protein Information

Name CA3
Synonyms CA III; Carbonic anhydrase C; CA3; CAIII; Car3; Carbonate dehydratase III; Carbonic anhydrase 3; Carbonic anhydrase III…

Compound Information

Name cycloheximide
CAS

Reference List

PubMed Abstract RScore(About this table)
19545598 Gordon RY, Mugantseva EA, Khutzian SS, Podolski IY: Cycloheximide-induced inhibition of protein synthesis in hippocampal pyramidal neurons is time-dependent: differences between CA1 and CA3 areas. Neurosci Lett. 2009 Sep 25;461(3):249-51. Epub 2009 Jun 21.
85(1,1,1,5) Details
18184892 Young SR, Bianchi R, Wong RK: Signaling mechanisms underlying group I mGluR-induced persistent AHP suppression in CA3 hippocampal neurons. J Neurophysiol. 2008 Mar;99(3):1105-18. Epub 2008 Jan 9.

Preincubation of slices in inhibitors of protein synthesis (cycloheximide or anisomycin) prevented the persistent suppression of AHPs by DHPG.
1(0,0,0,1) Details
18804535 Jimenez-Mateos EM, Hatazaki S, Johnson MB, Bellver-Estelles C, Mouri G, Bonner C, Prehn JH, Meller R, Simon RP, Henshall DC: Hippocampal transcriptome after status epilepticus in mice rendered seizure damage-tolerant by epileptic preconditioning features suppressed calcium and neuronal excitability pathways. Neurobiol Dis. 2008 Dec;32(3):442-53. Epub 2008 Sep 4.


Transcriptional changes in the hippocampal CA3 subfield of > or=2 fold were detected for 1357 genes in the tolerance group compared to a non-seizure control group, with 54% up-regulated.
1(0,0,0,1) Details