| Name | gelatinase B |
|---|---|
| Synonyms | 92 kDa gelatinase; Neutrophil collagenase; 92 kDa type IV collagenase; CLG4B; Collagenase type IV B; Collagenase type V; GEL B; GELB… |
| Name | cycloheximide |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18029162 | Sampieri CL, Nuttall RK, Young DA, Goldspink D, Clark IM, Edwards DR: Activation of p38 and JNK MAPK pathways abrogates requirement for new protein synthesis for phorbol ester mediated induction of select MMP and TIMP genes. Matrix Biol. 2008 Mar;27(2):128-38. Epub 2007 Oct 4. However, even though all inhibitors effectively blocked translation, PMA-induction of MMP9 and TIMP3 was blocked by emetine but was insensitive to cycloheximide and anisomycin. |
33(0,1,1,3) | Details |
| 17912438 | Peng ST, Su CH, Kuo CC, Shaw CF, Wang HS: CD44 crosslinking-mediated matrix metalloproteinase-9 relocation in breast tumor cells leads to enhanced metastasis. Int J Oncol. 2007 Nov;31(5):1119-26. |
2(0,0,0,2) | Details |
| 16967517 | Zhang X, Christenson LK, Nothnick WB: Regulation of MMP-9 expression and activity in the mouse uterus by Mol Reprod Dev. 2007 Mar;74(3):321-31. MMP-9/gelatinase B is one of the major MMPs found in the uterus that modulates uterine biology during various reproductive processes. Pretreatment with a transcription inhibitor actinomycin D or translation inhibitor cycloheximide indicates that E (2) regulates uterine MMP-9 at multiple points, involving transcriptional and posttranscriptional control as well as modulation of inhibitor activities. |
2(0,0,0,2) | Details |
| 16153722 | Fahling M, Steege A, Perlewitz A, Nafz B, Mrowka R, Persson PB, Thiele BJ: Role of nucleolin in posttranscriptional control of MMP-9 expression. Biochim Biophys Acta. 2005 Oct 15;1731(1):32-40. Epub 2005 Aug 29. Treating HT1080 cells, a human fibrosarcoma cell line, with the iron chelator 2,2-Dipyridyl, which mimics certain aspects of hypoxia, leads to a 3-fold elevated Matrix-metalloproteinase-9 (MMP-9) protein level. |
1(0,0,0,1) | Details |
| 16514055 | Gu BJ, Wiley JS: Rapid ATP-induced release of matrix metalloproteinase 9 is mediated by the P2X7 receptor. Blood. 2006 Jun 15;107(12):4946-53. Epub 2006 Mar 2. ATP-induced MMP-9 release was inhibited by the P2X (7) receptor antagonists periodate oxidized ATP and KN-62, or by chelators, as well as by a loss-of-function polymorphism in the P2X (7) receptor, but not by brefeldin A, monensin, or cycloheximide, or by anti-tumor necrosis factor-alpha (TNF-alpha) or anti-interleukin-1beta (IL-1beta) monoclonal antibodies. |
2(0,0,0,2) | Details |