| Name | HCAM |
|---|---|
| Synonyms | CD44; LHR; Heparan sulfate proteoglycan; CD44 antigen; CD44 antigen (Indian blood group); CD44 antigen (homing function and Indian blood group system); CD44 antigen precursor; CD44 molecule (Indian blood group)… |
| Name | cycloheximide |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17912438 | Peng ST, Su CH, Kuo CC, Shaw CF, Wang HS: CD44 crosslinking-mediated matrix metalloproteinase-9 relocation in breast tumor cells leads to enhanced metastasis. Int J Oncol. 2007 Nov;31(5):1119-26. |
12(0,0,0,12) | Details |
| 16945930 | Thankamony SP, Knudson W: Acylation of CD44 and its association with lipid rafts are required for receptor and endocytosis. J Biol Chem. 2006 Nov 10;281(45):34601-9. Epub 2006 Aug 30. Using cycloheximide to prevent de novo protein synthesis, palmitoylation-deficient mutants underwent slower turnover from cell surface compared with the palmitoylation-intact wild type, as determined by immunofluorescence and Western blotting. |
7(0,0,0,7) | Details |
| 18194670 | Gressner OA, Lahme B, Gressner AM: Gc-globulin (vitamin D binding protein) is synthesized and secreted by hepatocytes and internalized by hepatic stellate cells through Ca (2+)-dependent interaction with the megalin/gp330 receptor. Clin Chim Acta. 2008 Apr;390(1-2):28-37. Epub 2007 Dec 23. Cytoskeletal stainings of gc-globulin and alpha-smooth-muscle actin in hepatic stellate cells and the identification of the receptors megalin/gp330, HCAM/CD44, cubilin and annexin A2 were performed with confocal immunocytochemistry, immunoblotting and/or FACS-analysis. RESULTS: Hepatocytes synthesize and secrete gc-globulin as shown by RT-PCR and [(35) S]- labelling, which could be suppressed by cycloheximide. |
2(0,0,0,2) | Details |
| 19604397 | Hugo HJ, Wafai R, Blick T, Thompson EW, Newgreen DF: Staurosporine augments EGF-mediated EMT in PMC42-LA cells through actin depolymerisation, focal contact size reduction and Snail1 induction - a model for cross-modulation. BMC Cancer. 2009 Jul 15;9:235. Gene expression analysis by MT-PCR indicated that ST repressed many genes which were induced by EGF (EGFR, CAV1, CTGF, CYR61, CD44, S100A4) and induced genes which alter the actin cytoskeleton (NLF1, NLF2, EPHB4). METHODS: PMC42-LA cells were treated for 72 h with 10 ng/ml EGF, 40 nM ST, or both, and assessed for expression of E-cadherin repressor genes (Snail1, Snail2, Zeb1/deltaEF1) and EMT-related genes by QRT-PCR, multiplex tandem PCR (MT-PCR) and immunofluorescence +/- cycloheximide. |
1(0,0,0,1) | Details |