Protein Information

Name PGDS
Synonyms Glutathione dependent PGD synthetase; PGDS; Glutathione requiring prostaglandin D synthase; H PGDS; Hematopoetic prostaglandin D2 synthase; Hematopoietic prostaglandin D synthase; PGDS protein; PTGDS 2…

Compound Information

Name cycloheximide
CAS

Reference List

PubMed Abstract RScore(About this table)
19094210 Zayed N, Li X, Chabane N, Benderdour M, Martel-Pelletier J, Pelletier JP, Duval N, Fahmi H: Increased expression of lipocalin-type prostaglandin D2 synthase in osteoarthritic cartilage. Arthritis Res Ther. 2008;10(6):R146. Epub 2008 Dec 18.

The upregulation of L-PGDS by IL-1beta was blocked by the translational inhibitor cycloheximide, indicating that this effect is indirect, requiring de novo protein synthesis.
93(1,1,1,13) Details