Protein Information

Name aldose reductase
Synonyms ADR; ALDR 1; ALDR1; Aldehyde reductase; AKR1B1; AKR1B1 protein; AR; Aldehyde reductase 1…

Compound Information

Name cycloheximide
CAS

Reference List

PubMed Abstract RScore(About this table)
15936242 Lee YS, Paek KS, Kang ES, Jang HS, Kim HJ, Kang YJ, Kim JH, Lee HT, Lee JH, Chang KC, Nishinaka T, Seo HG: Involvement of nuclear factor kappaB in up-regulation of aldose reductase gene expression by 12-O-tetradecanoylphorbol-13-acetate in HeLa cells. Int J Biochem Cell Biol. 2005 Nov;37(11):2297-309.

9(0,0,0,9) Details
19422879 Liao CS, Tai PJ, Huang YH, Chen RN, Wu SM, Kuo LW, Yeh CT, Tsai MM, Chen WJ, Lin KH: Regulation of AKR1B1 by thyroid hormone and its receptors. . Mol Cell Endocrinol. 2009 Aug 13;307(1-2):109-17. Epub 2009 May 5.

6(0,0,0,6) Details
17584970 Ramana KV, Tammali R, Reddy AB, Bhatnagar A, Srivastava SK: Aldose reductase-regulated tumor necrosis factor-alpha production is essential for high glucose-induced vascular smooth muscle cell growth. Endocrinology. 2007 Sep;148(9):4371-84. Epub 2007 Jun 21.

The increase in TNF-alpha production was prevented by actinomycin D and cycloheximide, indicating transcriptional activation of TNF-alpha gene.
2(0,0,0,2) Details
15928807 Kang ES, Kim HJ, Paek KS, Jang HS, Chang KC, Lee JH, Nishinaka T, Yabe-Nishimura C, Seo HG: Phorbol ester up-regulates aldose reductase expression in A549 cells: a potential role for aldose reductase in cell cycle modulation. Cell Mol Life Sci. 2005 May;62(10):1146-55.

2(0,0,0,2) Details