| Name | growth hormone receptor |
|---|---|
| Synonyms | GH receptor; GHBP; GH receptors; GHR; Growth hormone receptor; Growth hormone receptor precursor; Somatotropin receptor; Growth hormone receptors… |
| Name | paraquat |
|---|---|
| CAS | 1,1′-dimethyl-4,4′-bipyridinium |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 12384824 | Hauck SJ, Aaron JM, Wright C, Kopchick JJ, Bartke A: Antioxidant enzymes, free-radical damage, and response to paraquat in liver and kidney of long-living growth hormone receptor/binding protein gene-disrupted mice. Horm Metab Res. 2002 Sep;34(9):481-6. |
62(0,2,2,2) | Details |
| 16713617 | Harper JM, Salmon AB, Chang Y, Bonkowski M, Bartke A, Miller RA: Stress resistance and aging: influence of genes and nutrition. Mech Ageing Dev. 2006 Aug;127(8):687-94. Epub 2006 May 19. Previous studies have shown that dermal fibroblast cell lines derived from young adult mice of the long-lived Snell dwarf (dw/dw), Ames dwarf (df/df) and growth hormone receptor knockout (GHR-KO) mouse stocks are resistant, in vitro, to the cytotoxic effects of peroxide, cadmium, ultraviolet light, paraquat, and heat. |
6(0,0,1,1) | Details |
| 19786089 | Sun LY, Steinbaugh MJ, Masternak MM, Bartke A, Miller RA: Fibroblasts from long-lived mutant mice show diminished ERK1/2 phosphorylation but exaggerated induction of immediate early genes. Free Radic Biol Med. 2009 Dec 15;47(12):1753-61. Epub 2009 Sep 26. Skin-derived fibroblasts from long-lived mutant mice, including the Snell dwarf mice and mice defective in growth hormone receptor (GHRKO mice), are resistant to death induced by oxidative stress or by UV light, but the molecular mechanism for their stress resistance is unknown. This study shows that phosphorylation of the stress-activated protein kinases ERK1/2 induced by peroxide, cadmium, or paraquat is attenuated in cells from these mice. |
1(0,0,0,1) | Details |
| 15701676 | Salmon AB, Murakami S, Bartke A, Kopchick J, Yasumura K, Miller RA: Fibroblast cell lines from young adult mice of long-lived mutant strains are resistant to multiple forms of stress. Am J Physiol Endocrinol Metab. 2005 Jul;289(1):E23-9. Epub 2005 Feb 8. Previous studies have shown that dermal fibroblast cell lines derived from young adult mice of the long-lived Snell dwarf mutant stock are resistant, in vitro, to the cytotoxic effects of H (2) O (2), cadmium, UV light, paraquat, and heat. |
0(0,0,0,0) | Details |