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Zurich MG, Honegger P, Schilter B, Costa LG, Monnet-Tschudi F: Use of aggregating brain cell cultures to study developmental effects of organophosphorus insecticides. Neurotoxicology. 2000 Aug;21(4):599-605.
To study the developmental toxicity of organophosphorus compounds (OP), aggregating brain cell cultures were treated with parathion.
In contrast, uridine incorporation and myelin basic protein (MBP) immunoreactivity revealed strong differences in sensitivity between these two developmental stages. |
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