Protein Information

Name calmodulin
Synonyms CALM; CAM; CALM 1; CALM 2; CALM 3; CALM1; CALM2; CALM3…

Compound Information

Name parathion
CAS

Reference List

PubMed Abstract RScore(About this table)
1380492 Nayeemunnisa, Begum S: Methyl parathion induced regional alterations in the regulatory proteins during critical stage of central nervous system development in albino rat pups. Indian J Physiol Pharmacol. 1992 Apr;36(2):77-82.

Sublethal doses of methyl parathion (O,O-dimethyl-O-nitrophenyl- thiophosphate) injected intraperitoneally to 15 and 21 day old rat pups induced regional alterations in the central nervous system (CNS) in the levels of total RNA, total proteins, modulatory protein Calmodulin (CaM), in the activity levels of membrane bound enzyme Ca (2+)-ATPase and phospholipids.
43(0,1,3,3) Details
1761796 Pala I, Vig PJ, Desaiah D, Srinivasan A: In vitro effects of organophosphorus compounds on calmodulin activity. J Appl Toxicol. 1991 Dec;11(6):391-5.

In vitro effects of organophosphorus compounds (OP), such as malathion (M), methyl parathion (MP) and ethyl parathion (EP), on calmodulin (CaM) activity and its active conformation were studied to understand the mechanism (s) of neurotoxicity, since CaM is known to regulate Ca2+ transport and the enzymes involved in signal transduction and nucleotide metabolism.
34(0,1,1,4) Details