Protein Information

Name glutathione reductase
Synonyms GLUR; GR; GRD 1; GRD1; GRase; GSR; Glutathione reductase; GRases…

Compound Information

Name copper sulfate
CAS sulfuric acid copper(2+) salt (1:1)

Reference List

PubMed Abstract RScore(About this table)
17561779 Razinger J, Dermastia M, Drinovec L, Drobne D, Zrimec A, Koce JD: Antioxidative responses of duckweed (Lemna minor L.) to short-term copper exposure. Environ Sci Pollut Res Int. 2007 May;14(3):194-201.


Glutathione concentration and enzymatic activities of catalase, guaiacol peroxidase and glutathione reductase were measured spectrophotometrically.
4(0,0,0,4) Details
9075838 Hussein O, Rosenblat M, Refael G, Aviram M: Dietary selenium increases cellular glutathione peroxidase activity and reduces the enhanced susceptibility to lipid peroxidation of plasma and low-density lipoprotein in kidney transplant recipients. Transplantation. 1997 Mar 15;63(5):679-85.


Analyses of the patients' red blood cell (RBC) glutathione system revealed low levels of reduced glutathione and decreased activities of RBC glutathione peroxidase and glutathione reductase by 23%, 18%, and 20%, respectively, in comparison to normal RBC.
2(0,0,0,2) Details
19665240 Wu TM, Hsu YT, Sung MS, Hsu YT, Lee TM: Expression of genes involved in redox homeostasis and antioxidant defense in a marine macroalga Ulva fasciata by excess copper. Aquat Toxicol. 2009 Oct 4;94(4):275-85. Epub 2009 Jul 19.


Phycologia 47, 346-360] were cloned and their expression was compared to superoxide dismutase (UfMnsod and UfFesod), ascorbate peroxidase (UfApx), glutathione reductase (UfGr), and catalase (UfCat).
1(0,0,0,1) Details
15992939 Dewez D, Geoffroy L, Vernet G, Popovic R: Determination of photosynthetic and enzymatic biomarkers sensitivity used to evaluate toxic effects of copper and fludioxonil in alga Scenedesmus obliquus. Aquat Toxicol. 2005 Aug 30;74(2):150-9.


Under the same condition, enzymatic activities of catalase, ascorbate peroxidase, glutathione reductase and glutathione S-transferase were investigated to evaluate antioxidative response to fungicides effects.
1(0,0,0,1) Details
6810885 Rafter GW: Copper inhibition of glutathione reductase and its reversal with gold thiolates, thiol, and disulfide compounds. Biochem Med. 1982 Jun;27(3):381-91.

1(0,0,0,1) Details
10816044 Fernandes AR, Prieto M, Sa-Correia I: Modification of plasma membrane lipid order and H+-ATPase activity as part of the response of Saccharomyces cerevisiae to cultivation under mild and high copper stress. Arch Microbiol. 2000 Apr;173(4):262-8.


The adaptive mechanisms examined in this study included the coordinate increase in the activities of Cu,Zn-superoxide dismutase (up to five-fold), glutathione reductase (up to 1.7-fold), and plasma membrane H+-ATPase (up to three-fold).
1(0,0,0,1) Details