Protein Information

Name catalase
Synonyms CAT; Catalase; Erythrocyte derived growth promoting factor; Carnitine O acetyltransferase; Carnitine acetylase; Carnitine acetyltransferase; CAT; Catalases…

Compound Information

Name parathion
CAS

Reference List

PubMed Abstract RScore(About this table)
16675014 Bianchini A, Monserrat JM: Effects of methyl parathion on Chasmagnathus granulatus hepatopancreas: protective role of sesamol. Ecotoxicol Environ Saf. 2007 May;67(1):100-8. Epub 2006 May 3.

Antioxidant enzyme activities (catalase and glutathione S-transferase) and lipid peroxidation (LPO) levels were also increased in hepatopancreas of crabs injected with methyl parathion.
6(0,0,1,1) Details
16933622 Jiang YJ, Deng YJ, Liu XR, Xie BG, Hu FP: [Isolation and identification of a bacterial strain JS018 capable of degrading several kinds of organophosphate pesticides]. Wei Sheng Wu Xue Bao. 2006 Jun 4;46(3):463-6.

The catalase, urease and nitrate reduction were positive.
Laboratory tests showed that the bacterium could degrade several kinds of organophosphate pesticides, such as Parathion-methyl and phoxin.
1(0,0,0,1) Details
18655848 Monteiro DA, Rantin FT, Kalinin AL: The effects of selenium on oxidative stress biomarkers in the freshwater characid fish matrinxa, Brycon cephalus (Gunther, 1869) exposed to organophosphate insecticide Folisuper 600 BR (methyl parathion). Comp Biochem Physiol C Toxicol Pharmacol. 2009 Jan;149(1):40-9. Epub 2008 Jul 4.

Catalase (CAT), glutathione peroxidase (GPx), superoxide dismutase (SOD), glutathione S-transferase (GST), reduced glutathione (GSH) and lipid peroxidation (LPO) levels in the gills, white muscle and liver were evaluated in fish fed on diets containing 0 or 1.5 mg Se kg (-1) for 8 weeks.
1(0,0,0,1) Details
16510128 Patel S, Singh V, Kumar A, Gupta YK, Singh MP: Status of antioxidant defense system and expression of toxicant responsive genes in striatum of maneb- and paraquat-induced Parkinson's disease phenotype in mouse: mechanism of neurodegeneration. Brain Res. 2006 Apr 7;1081(1):9-18. Epub 2006 Feb 28.

The involvement of cytochrome P4502E1 and glutathione S-transferases A4-4 enzymes in the detoxification of several pesticides such as atrazine, fenamirol, organophosphorous insecticide parathion, methoxychlor, diethyl dithiocarbamate and paraquat has been known.
A significant increase in catalase, glutathione S-transferase and lipid peroxidation in the striatum was found following 3, 6 and 9 weeks of co-treatment as compared with individual treatment or controls.
1(0,0,0,1) Details
16546452 Monteiro DA, de Almeida JA, Rantin FT, Kalinin AL: Oxidative stress biomarkers in the freshwater characid fish, Brycon cephalus, exposed to organophosphorus insecticide Folisuper 600 (methyl parathion). Comp Biochem Physiol C Toxicol Pharmacol. 2006 Jun;143(2):141-9. Epub 2006 Mar 20.

The effect of a single exposure to 2 mg L (- 1) of a commercial formulation of MP (MPc: Folisuper 600 (R), MP 600 g L (- 1)) on catalase (CAT), glutathione peroxidase (GPx), superoxide dismutase (SOD), glutathione S-transferase (GST), reduced glutathione (GSH) and lipid peroxidation (LPO) of the liver, white muscle and gills of Brycon cephalus was evaluated after 96 h of treatment.
1(0,0,0,1) Details
7800659 Pasquini R, Scassellati-Sforzolini G, Dolara P, Pampanella L, Villarini M, Caderni G, Fazi M, Fatigoni C: Assay of linuron and a pesticide mixture commonly found in the Italian diet, for promoting activity in rat liver carcinogenesis. Pharmacol Toxicol. 1994 Sep-Oct;75(3-4):170-6.

Composition of the pesticide mixture was: benomyl (19.55%); dithiocarbamates (20.67%); thiabendazole (14.94%); diphenylamine (14.25%); chlorthalonil (13.13%); procymidone (7.96%); fenarimol (1.95%); chlorpropham (0.70%); vinchlozolin (0.28%); methidathion (2.37%); chlorpyriphos-ethyl (2.09%); parathionmethyl (1.00%); chlorfenvinphos (0.27%); parathion (0.70%); pyrimiphos-ethyl (0.14%).
To determine promoting activity we evaluated induction of preneoplastic foci in diethylnitrosamine-initiated hepatocytes, by positive gammaglutamyl-transpeptidase (GGTase) staining in liver slides, and peroxisome proliferation by peroxisomal-dependent catalase and palmitoyl-CoA-oxidase dosage.
1(0,0,0,1) Details