| Name | 5 hydroxytryptamine 4 receptor |
|---|---|
| Synonyms | 5 HT4; serotonin receptor; 5 hydroxytryptamine 4 receptor; 5 hydroxytryptamine receptor 4; 5 HT 4; 5 HT4R; 5 hydroxytryptamine (serotonin) receptor 4; Cardiac 5 HT4 receptor… |
| Name | copper sulfate |
|---|---|
| CAS | sulfuric acid copper(2+) salt (1:1) |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10688616 | Yamakuni H, Sawai H, Maeda Y, Imazumi K, Sakuma H, Matsuo M, Mutoh S, Seki J: Probable involvement of the 5-hydroxytryptamine (4) receptor in methotrexate-induced delayed emesis in dogs. J Pharmacol Exp Ther. 2000 Mar;292(3):1002-7. Copper sulfate-induced emesis in dogs was also prevented by FK1052, tropisetron, and CP-122,721 but not by |
3(0,0,0,3) | Details |
| 1663456 | Bhandari P, Andrews PL: Preliminary evidence for the involvement of the putative 5-HT4 receptor in zacopride- and sulphate-induced vomiting in the ferret. Eur J Pharmacol. 1991 Nov 12;204(3):273-80. |
1(0,0,0,1) | Details |
| 8082706 | Fukui H, Yamamoto M, Sasaki S, Sato S: Possible involvement of peripheral 5-HT4 receptors in copper sulfate-induced vomiting in dogs. Eur J Pharmacol. 1994 May 12;257(1-2):47-52. |
324(4,4,4,4) | Details |
| 9085045 | Minami M, Endo T, Tamakai H, Ogawa T, Hamaue N, Hirafuji M, Monma Y, Yoshioka M, Hagihara K: Antiemetic effects of N-3389, a newly synthesized 5-HT3 and 5-HT4 receptor antagonist, in ferrets. Eur J Pharmacol. 1997 Mar 5;321(3):333-42. The antiemetic activity of N-3389 (endo-3,9-dimethyl-3,9-diazabicyclo [3,3,1] non-7-yl-1 H-indazole-3-carboxamide dihydrochloride), a new 5-HT3 and 5-HT4 receptor antagonist, against cisplatin-, cyclophosphamide- and copper sulfate-induced emesis was investigated using ferrets. |
33(0,1,1,3) | Details |
| 16079468 | Nakayama H, Yamakuni H, Higaki M, Ishikawa H, Imazumi K, Matsuo M, Mutoh S: Antiemetic activity of FK1052, a 5-HT3- and 5-HT4-receptor antagonist, in Suncus murinus and ferrets. J Pharmacol Sci. 2005 Aug;98(4):396-403. Epub 2005 Jul 29. We investigated the effect of FK1052 [(+)-8,9-dihydro-10-methyl-7-[(5-methyl-1H--4-yl) methyl] pyrido [1,2 -a] indol-6 (7H)-one hydrochloride], a 5-HT3- and 5-HT4-receptor antagonist, on the emesis induced by motion stimuli, copper sulfate, or cisplatin in either Suncus murinus or ferrets and also clarified the role of the 5-HT3 and 5-HT4 receptors in these models. |
32(0,1,1,2) | Details |