Protein Information

Name MCM2
Synonyms CDABP0042; MCM 2; MCM2; CDC47; CDC47 homolog; DNA replication licensing factor MCM7; MCM 7; MCM7…

Compound Information

Name parathion
CAS

Reference List

PubMed Abstract RScore(About this table)
18204794 Calaf GM, Roy D: Cancer genes induced by malathion and parathion in the presence of estrogen in breast cells. Int J Mol Med. 2008 Feb;21(2):261-8.

Expression of the HSP 27, MCM2 and TP53 inducible protein 3 genes was up-regulated with malathion alone and with the combination of estrogen and either malathion or parathion while TP53 (Li-Fraumeni syndrome) was up-regulated by estrogen alone and malathion alone.
6(0,0,1,1) Details
17390078 Calaf GM, Roy D: Gene expression signature of parathion-transformed human breast epithelial cells. Int J Mol Med. 2007 May;19(5):741-50.

Among the genes affected were the cyclins, such as cyclin D3, the cyclin-dependent kinases (CDKs) such as CDK41 and the minichromosome maintenance deficient (MCM) MCM2 and MCM3.
1(0,0,0,1) Details