| Name | G proteins |
|---|---|
| Synonyms | G gamma I; Guanine nucleotide binding protein 2; G protein; GNG 2; GNG2; GNGT 2; GNGT2; Guanine nucleotide binding protein gamma 2… |
| Name | parathion |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 20298678 | Adigun AA, Ryde IT, Seidler FJ, Slotkin TA: Organophosphate Exposure During a Critical Developmental Stage Reprograms Adenylyl Cyclase Signaling in PC12 Cells. Brain Res. 2010 Mar 15. We exposed PC12 cells to chlorpyrifos, diazinon or parathion in the undifferentiated state and during neurodifferentiation; we then assessed the function of the adenylyl cyclase (AC) signaling cascade, measuring basal AC activity as well as responses to stimulants acting at G-proteins or on the AC molecule itself. |
31(0,1,1,1) | Details |
| 20074626 | Adigun AA, Wrench N, Levin ED, Seidler FJ, Slotkin TA: Neonatal parathion exposure and interactions with a high-fat diet in adulthood: Adenylyl cyclase-mediated cell signaling in heart, liver and cerebellum. Brain Res Bull. 2010 Apr 5;81(6):605-12. Epub 2010 Jan 14. One common mechanism is disrupted cell signaling mediated through cyclic AMP, targeting neurohumoral receptors, G-proteins and adenylyl cyclase (AC) itself. |
1(0,0,0,1) | Details |
| 15889724 | Icen E, Armutcu F, Buyukguzel K, Gurel A: Biochemical stress indicators of greater wax moth exposure to organophosphorus insecticides. J Econ Entomol. 2005 Apr;98(2):358-66. We observed a significant higher increase in MDA content in the larvae reared with 10 ppm EP (102.16 +/- 1.57 nmol/g protein) than the control group (30.28 +/- 1.42 nmol/g protein). We therefore investigated alterations in lipid peroxidation product, malondialdehyde (MDA) content, and alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities, in conjunction with AChE activity as biochemical stress indicators in greater wax moth, Galleria mellonella (L.) larvae for OPs methyl parathion (MP) and ethyl parathion (EP). |
1(0,0,0,1) | Details |
| 20123610 | Adigun AA, Wrench N, Seidler FJ, Slotkin TA: Neonatal organophosphorus pesticide exposure alters the developmental trajectory of cell-signaling cascades controlling metabolism: differential effects of diazinon and parathion. Environ Health Perspect. 2010 Feb;118(2):210-5. RESULTS: In the liver, DZN elicited global sensitization, characterized by parallel up-regulation of AC activity itself and of the responses to stimulants acting at beta-adrenergic receptors, glucagon receptors, or G-proteins. |
1(0,0,0,1) | Details |