| Name | cytochrome c |
|---|---|
| Synonyms | CYC; CYCS; Cytochrome C; HCS; Cytochrome Cs |
| Name | parathion |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15813 | Yoshihara S, Neal RA: Comparison of the metabolism of parathion by a rat liver reconstituted mixed-function oxidase enzyme system and by a system containing cumene hydroperoxide and purified rat liver cytochrome P-450. Drug Metab Dispos. 1977 Mar-Apr;5(2):191-7. The metabolism of parathion by a reconstituted mixed-function oxidase enzyme system (rat liver cytochrome P-450, -cytochrome c reductase, dilauroyl and or a cumene hydroperoxide system (cytochrome P-450, dilauroyl and cumene hydroperoxide) have been compared. |
81(1,1,1,1) | Details |
| 2769697 | Chambers JE, Forsyth CS: Lack of inducibility of brain monooxygenase activities including parathion desulfuration. J Biochem Toxicol. 1989 Spring;4(1):65-70. The ability of phenobarbital and beta-naphthoflavone to induce parathion desulfuration, aminopyrine N-demethylation, and -cytochrome-c reductase activity in the brain and liver of male and female rats was investigated. |
31(0,1,1,1) | Details |
| 12831782 | Saleh AM, Vijayasarathy C, Masoud L, Kumar L, Shahin A, Kambal A: Paraoxon induces apoptosis in EL4 cells via activation of mitochondrial pathways. Toxicol Appl Pharmacol. 2003 Jul 1;190(1):47-57. Recently, we have shown that, at noncholinergic doses (1 to 10 nM), POX (the bioactive metabolite of parathion) causes apoptotic cell death in murine EL4 T-lymphocytic leukemia cell line through activation of caspase-3. Indeed, under both in vitro and in vivo conditions, POX triggered a dose- and time-dependent translocation of cytochrome c from mitochondria into the cytosol, as assessed by Western blot analysis. |
3(0,0,0,3) | Details |
| 16222729 | Dietrich M, Grundmann L, Kurr K, Valinotto L, Saussele T, Schmid RD, Lange S: Recombinant production of human microsomal cytochrome P450 2D6 in the methylotrophic yeast Pichia pastoris. Chembiochem. 2005 Nov;6(11):2014-22. CPR activity was detected by conversion of cytochrome c by using isolated microsomes. Microsomes containing human CPR and CYP2D6 converted different substrates, such as 3-cyano-7-ethoxycoumarin, parathion and dextrometorphan. |
1(0,0,0,1) | Details |