| Name | NADPH cytochrome P450 reductase |
|---|---|
| Synonyms | CPR; CYPOR; Cytochrome P 450 reductase; Cytochrome P450 reductase; NADPH cytochrome P450 reductase; NADPH cytochrome P450 reductase; P450 (cytochrome) oxidoreductase; P450R… |
| Name | parathion |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 7696534 | Murray M, Butler AM: Hepatic biotransformation of parathion: role of cytochrome P450 in - and -mediated microsomal oxidation in vitro. Chem Res Toxicol. 1994 Nov-Dec;7(6):792-9. An anti-NADPH-cytochrome P450 reductase -P450 reductase) antibody partially inhibited microsomal parathion oxidation mediated by either cofactor, and the P450 inhibitor was similarly effective against the - and -supported oxidation of parathion. |
81(1,1,1,1) | Details |
| 3983973 | Levi PE, Hodgson E: Oxidation of pesticides by purified cytochrome P-450 isozymes from mouse liver. Toxicol Lett. 1985 Feb-Mar;24(2-3):221-8. 5 cytochrome P-450 isozymes were purified from the livers of uninduced mice and reconstituted with purified cytochrome P-450 reductase and phospholipid. The pesticides parathion, fonofos, DEF, Mocap and profenofos were oxidized by the reconstituted monooxygenase system to form acetylcholinesterase (AChE) inhibitors. |
1(0,0,0,1) | Details |
| 859108 | Davis JE, Mende TJ: A study of the binding of to rat liver microsomes which occurs concurrently with the metabolism of O, O-diethyl O-p-nitrophenyl phosphorothioate (parathion) to O, O-diethyl O-p-nitrophenyl (paraoxon). J Pharmacol Exp Ther. 1977 May;201(2):490-7. Preliminary investigations revealed similar binding occurs when the microsomal preparation is replaced with purified rabbit cytochrome P-450 plus -cytochrome P-450 reductase and |
1(0,0,0,1) | Details |