| Name | transferase |
|---|---|
| Synonyms | 4' phosphopantetheinyl transferase; 4' phosphopantetheinyl transferase; AASD PPT; AASDHPPT; AASDPPT; Alpha aminoadipic semialdehyde dehydrogenase phosphopantetheinyl transferase; Aminoadipate semialdehyde dehydrogenase phosphopantetheinyl transferase; CGI 80… |
| Name | parathion |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 2570559 | Sonnenschein P, Golbs S, Weigel B, Wiezorek WD: [The fermentation diagnosis and histologic studies in blood and the liver of surviving rats after 1 and 2 administrations of a median toxic dose of parathion methyl. 2. Arch Exp Veterinarmed. 1989 Jan;43(1):9-15. -amino transferase, an enzyme induced to the liver via glucocorticoids, caused clearly measurable activity rises in either sex, 24 hours after 1 and 2 applications. |
1(0,0,0,1) | Details |
| 2042734 | Tracy JW, O'Leary KA: Analysis of glutathione S-transferase-catalyzed S-alkylglutathione formation by high-performance liquid chromatography. Anal Biochem. 1991 Feb 15;193(1):1-5. The utility of the method is illustrated by the use of partially purified preparations of rat liver glutathione S-transferases and several prototypic substrates including iodomethane, iodoethane, dichlorvos, and methyl parathion. Advantages of the method over other assays of S-alkyl transferase activity are discussed. |
1(0,0,0,1) | Details |
| 7722883 | Lodovici M, Aiolli S, Monserrat C, Dolara P, Medica A, Di Simplicio P: Effect of a mixture of 15 commonly used pesticides on DNA levels of and xenobiotic metabolizing enzymes in rat liver. J Environ Pathol Toxicol Oncol. 1994;13(3):163-8. The level of 8-OH- in rat liver DNA was measured as an index of oxidative damage after treating rats for 10 days at a dose ranging from 0.75 to 10 mg/kg with a mixture of 15 pesticides (dithiocarbamate, benomyl, thiabendazole, diphenylamine, chlorthalonil, procimidone, methidathion, chlorpyrifos-ethyl, fenarimol, parathion-methyl, chlorpropham, parathion, vinclozolin, chlorfenvinphos, pirimiphos-ethyl) commonly found in foods of central Italy. The administration of the pesticide mixture dose dependently reduced benzo (a) pyrene hydroxylase, N-demethylase activities, peroxidase, glutathione reductase, glutathione-S-transferase and thiol transferase activities in the liver. |
1(0,0,0,1) | Details |
| 10771139 | Ait-Aissa S, Porcher J, Arrigo A, Lambre C: Activation of the hsp70 promoter by environmental inorganic and organic chemicals: relationships with cytotoxicity and lipophilicity. Toxicology. 2000 Apr 14;145(2-3):147-57. For this purpose, we used an established HeLa cell line containing the chloramphenicol acetyl transferase (CAT) gene under the control of the hsp70 promoter. Some organochlorine compounds (chlorophenol derivatives, tetrachlorohydroquinone, 3, 4-dichloroaniline, ethyl parathion and 1-chloro-2,4-dinitrobenzene) induced a response, whereas other common halogenated pesticides or aromatic hydrocarbons (e.g. benzo (a) pyrene, 2, 4-dichlorophenoxyacetic acid, endosulfan, diuron, 4-nonylphenol) did not. |
1(0,0,0,1) | Details |
| 11166672 | Anguiano OL, Caballero de Castro A, Pechen de D'Angelo AM: The role of conjugation in the regulation of early toad embryos' tolerance to pesticides. Comp Biochem Physiol C Toxicol Pharmacol. 2001 Jan;128(1):35-43. Reduced (GSH) content and glutathione S-transferase (GSH S-transferase) activity were investigated in developing toad embryos exposed to parathion, malathion, lindane and dieldrin. |
33(0,1,1,3) | Details |
| 7946013 | Zhu S, Liu YG: Toxicity and toxicokinetics of MeISP in isolated rat hepatocytes. . Biomed Environ Sci. 1994 Jun;7(2):169-79. It was found that at the final concentration of 1.5 mmol/L, MeISP can (1) result in an increase of leakage of intracellular enzymes, amino-transferase (ALT), lactate dehydrogenase (LDH), beta-glucuronidase (beta-GDase) and acid phosphatase (AcP) to the medium in a dose-dependent fashion; (2) give rise to obvious plasma membrane blebbing; (3) rapidly deplete the intracellular GSH and (4) almost completely inhibit the protein synthesis and gluconeogenesis from |
1(0,0,0,1) | Details |
| 6498609 | Rattner BA, Franson JC: Methyl parathion and fenvalerate toxicity in American kestrels: acute physiological responses and effects of cold. Can J Physiol Pharmacol. 1984 Jul;62(7):787-92. Fenvalerate, at doses far exceeding those encountered in the environment, caused mild intoxication and elevated plasma amino-transferase activity. |
1(0,0,0,1) | Details |
| 8359836 | Mahaboob Basha P, Nayeemunnisa: Methyl parathion induced alterations in GABAergic system during critical stage of central nervous system development in albino rat pups. Indian J Exp Biol. 1993 Apr;31(4):369-72. An increase in the activity levels of the enzymes glutamic acid decarboxylase and --amino transferase in the cortex, brain stem and spinal cord of the CNS was found. |
1(0,0,0,1) | Details |
| 2570558 | Sonnenschein P, Golbs S, Wiezorek WD: [The fermentation diagnosis and histologic studies in blood and the liver of surviving rats after 1 and 2 administrations of a median toxic dose of parathion methyl. 1. Arch Exp Veterinarmed. 1989 Jan;43(1):1-8. The most strongly pronounced rise was in activity of -amino transferase and was recorded from both sexes. |
1(0,0,0,1) | Details |
| 15612566 | Taskin V, Kence M: The genetic basis of malathion resistance in housefly (Musca domestica L.) strains from Turkey. Genetika. 2004 Nov;40(11):1475-82. Organophosphate insecticide (parathion/diazinon) resistance in housefly (Musca domestica L.) is associated with the change in carboxylesterase activity. In addition, we checked the malathion carboxylesterase (MCE), percent remaining activities in acetylcholinesterase (AChE), -S-transferase (GST), and general esterase activities in all 5 strains used in this study. |
1(0,0,0,1) | Details |
| 2430350 | Kashyap SK: Health surveillance and biological monitoring of pesticide formulators in India. Toxicol Lett. 1986 Oct;33(1-3):107-14. Exposure of 160 workers to a combination of pesticides (malathion, parathion, DDT and HCH) resulted in 73% of the workers showing toxic signs and symptoms. Changes in the liver enzymes carbamyl transferase (OCT), gamma-glutamyl transpeptidase (GGTP), leucine aminopeptidase (LAP) and in immunoglobulin M (IgM) showed possible effects on liver and humoral immunity. |
1(0,0,0,1) | Details |