Protein Information

Name glutathione transferase
Synonyms GST class mu 2; GST 4; GST4; GSTM; GSTM 2; GSTM2; GSTM2 2; GSTmu3…

Compound Information

Name parathion
CAS

Reference List

PubMed Abstract RScore(About this table)
3530629 Wood E, Casabe N, Melgar F, Zerba E: Distribution and properties of glutathione S-transferase from T. infestans. Comp Biochem Physiol B. 1986;84(4):607-17.

The glutathione transferase from T. infestans is able to render aqueous metabolites when incubated in vitro with malathion, parathion and fenitrothion.
31(0,1,1,1) Details
6205424 Costa LG, Murphy SD: Interaction between acetaminophen and organophosphates in mice. Res Commun Chem Pathol Pharmacol. 1984 Jun;44(3):389-400.


This study was undertaken to investigate whether depletion of hepatic nonprotein sulfhydryls (NPSH) by acetaminophen would potentiate the toxicity of organophosphates which are detoxified by glutathione transferases.
1(0,0,0,1) Details
8703089 Syvanen M, Zhou Z, Wharton J, Goldsbury C, Clark A: Heterogeneity of the glutathione transferase genes encoding enzymes responsible for insecticide degradation in the housefly. J Mol Evol. 1996 Sep;43(3):236-40.

One of the four glutathione-S-transferases (GST) that is overproduced in the insecticide-resistant Cornell-R strain of the housefly (Musca domestica) produces an activity that degrades the insecticide dimethyl parathion and conjugates glutathione to lindane.
1(0,0,0,1) Details
7725348 Di Ilio C, Sacchetta P, Iannarelli V, Aceto A: Binding of pesticides to alpha, mu and pi class glutathione transferase. . Toxicol Lett. 1995 Mar;76(2):173-7.

The binding of fluorodifen, fenarimol, acifluorfen, 2,4-DES, methyl parathion, paraquat and pyrazophos by alpha, mu and pi class glutathione transferases (GST) was determined by the 2-p-toluidinylnaphthalene-6-sulphonate (TNS) binding fluorescence inhibition technique.
32(0,1,1,2) Details