Protein Information

Name beta adrenergic receptor (protein family or complex)
Synonyms Beta adrenoceptor; Beta adrenoceptor; Beta adrenergic receptor; Beta adrenergic receptors; Beta adrenoceptor; Beta adrenoceptors; Beta adrenoceptors

Compound Information

Name parathion
CAS

Reference List

PubMed Abstract RScore(About this table)
10685507 Attia AM: Possible involvement of beta-adrenergic receptors in the enhancement of nocturnal pineal N-acetyltransferase activity due to parathion administration. Toxicology. 2000 Jan 3;142(2):79-86.

The results are consistent with the idea that parathion influences pineal 5-HT metabolism either at the level of the beta-adrenergic receptor or via the sympathetic innervation to the pineal gland.
149(1,3,4,4) Details
7716784 Attia AM, Mostafa MH, Richardson BA, Reiter RJ: Changes in nocturnal pineal indoleamine metabolism in rats treated with parathion are prevented by beta-adrenergic antagonist administration. Toxicology. 1995 Mar 31;97(1-3):183-9.

The results are consistent with the idea that parathion influences pineal 5-HT metabolism either at the level of the beta-adrenergic receptor or via the sympathetic innervation to the pineal gland.
143(1,3,3,3) Details
20074626 Adigun AA, Wrench N, Levin ED, Seidler FJ, Slotkin TA: Neonatal parathion exposure and interactions with a high-fat diet in adulthood: Adenylyl cyclase-mediated cell signaling in heart, liver and cerebellum. Brain Res Bull. 2010 Apr 5;81(6):605-12. Epub 2010 Jan 14.

Receptors controlling AC activity were also affected: beta-adrenergic receptors (betaARs) in skeletal muscle were increased, whereas those in the heart were decreased, and the latter also showed an elevation of m (2)-muscarinic acetylcholine receptors, which inhibit AC.
1(0,0,0,1) Details
20123610 Adigun AA, Wrench N, Seidler FJ, Slotkin TA: Neonatal organophosphorus pesticide exposure alters the developmental trajectory of cell-signaling cascades controlling metabolism: differential effects of diazinon and parathion. Environ Health Perspect. 2010 Feb;118(2):210-5.

RESULTS: In the liver, DZN elicited global sensitization, characterized by parallel up-regulation of AC activity itself and of the responses to stimulants acting at beta-adrenergic receptors, glucagon receptors, or G-proteins.
1(0,0,0,1) Details