Protein Information

Name TPMT
Synonyms 6 Mercaptopurine sensitivity; TPMT; Thiopurine S methyltransferase; Thiopurine methyltransferase; Thiopurine S methyltransferases; Thiopurine methyltransferases

Compound Information

Name parathion
CAS

Reference List

PubMed Abstract RScore(About this table)
17982697 Calaf GM, Roy D: Human drug metabolism genes in parathion-and estrogen-treated breast cells. Int J Mol Med. 2007 Dec;20(6):875-81.

Among the genes altered by parathion in comparison to the control were CHST5, CHST6 and CHST7 (sulfotransferases); CYP2F1, CYP3A7 and CYP4F3 (CYPs); GSTP1, GSTT2 and MGST1 (GSTs); MT1X (metallothionein); TPMT (methyltransferase); UGT1A1 and UGT2B (UDP glycosyltransferases).
12(0,0,2,2) Details