Protein Information

Name acid phosphatase
Synonyms ACP 3; PAP; ACP3; ACPP; ACPP protein; Acid phosphatase; Acid phosphatase prostate nirs variant 1; PACP…

Compound Information

Name parathion
CAS

Reference List

PubMed Abstract RScore(About this table)
3719134 Reddy PS, Bhagyalakshmi A, Ramamurthi R: Changes in acid phosphatase activity in tissues of crab, Oziotelphusa senex, following exposure to methyl parathion. Bull Environ Contam Toxicol. 1986 Jul;37(1):106-12.
6(0,0,1,1) Details
16783732 Narayana K, Prashanthi N, Nayanatara A, Kumar HH, Abhilash K, Bairy KL: Neonatal methyl parathion exposure affects the growth and functions of the male reproductive system in the adult rat. Folia Morphol. 2006 Feb;65(1):26-33.

Methyl parathion lowered the body weights from days 10 to 24 (p < 0.01), the weights of the reproductive organs (p < 0.05-0.01), the epididymal sperm count (p < 0.01) and the homogenisation-resistant testicular spermatid head count (p < 0.01) and also decreased acid phosphatase (ACP), cholesterol, uric acid, protein, ascorbic acid, and lactate dehydrogenase (p < 0.01) levels in the testis but only ACP and cholesterol in the epididymis.
6(0,0,1,1) Details
3952729 Abou-Donia MB, Abdo KM, Timmons PR, Proctor JE: Brain acetylcholinesterase, acid phosphatase, and 2',3'-cyclic nucleotide-3'-phosphohydrolase and plasma butyrylcholinesterase activities in hens treated with a single dermal neurotoxic dose of S,S,S-tri-n-butyl phosphorotrithioate. Toxicol Appl Pharmacol. 1986 Mar 15;82(3):461-73.

Three control groups consisted of hens left untreated, given a single, dermal dose of 500 mg/kg tri-o-cresyl phosphate (TOCP, positive control for organophophorous compound-induced delayed neurotoxicity), or 10 mg/kg O,O-diethyl O-4-nitrophenyl phosphorothioate (parathion, negative control).
2(0,0,0,2) Details
7946013 Zhu S, Liu YG: Toxicity and toxicokinetics of MeISP in isolated rat hepatocytes. . Biomed Environ Sci. 1994 Jun;7(2):169-79.


It was found that at the final concentration of 1.5 mmol/L, MeISP can (1) result in an increase of leakage of intracellular enzymes, alanine amino-transferase (ALT), lactate dehydrogenase (LDH), beta-glucuronidase (beta-GDase) and acid phosphatase (AcP) to the medium in a dose-dependent fashion; (2) give rise to obvious plasma membrane blebbing; (3) rapidly deplete the intracellular GSH and (4) almost completely inhibit the protein synthesis and gluconeogenesis from sodium pyruvate.
1(0,0,0,1) Details
2126817 Jabbar A, Khawaja SA, Iqbal A, Malik SA: Effect of malathion and methyl-parathion on rat liver enzymes. J Pak Med Assoc. 1990 Apr;40(4):85-9.

Short term (24 hr) and long term (4 weeks) treatment with insecticides resulted in increased specific activities of liver enzymes, Acid phosphatase, Alkaline phosphatase, Glutamate dehydrogenase, Glutamate oxaloacetate transaminase and Glutamate pyruvate transaminase.
1(0,0,0,1) Details
17171610 Prashanthi N, Narayana K, Nayanatara A, Chandra Kumar HH, Bairy KL, D'Souza UJ: The reproductive toxicity of the organophosphate pesticide 0, 0-dimethyl 0-4-nitrophenyl phosphorothioate (methyl parathion) in the male rat. Folia Morphol. 2006 Nov;65(4):309-21.

Biochemical estimates of acid phosphatase (ACP), cholesterol, total protein, uric acid, and vitamin C were conducted in the epididymes.
1(0,0,0,1) Details
2126808 Jabbar A, Khawaja SA, Iqbal A, Malik SA: Effect of malathion and methyl-parathion on rat liver enzymes. J Pak Med Assoc. 1990 Nov;40(11):266-70.

Short term (24 hr.) and long term (4 weeks) treatment with insecticides resulted in increased specific activities of liver enzymes, Acid phosphatase, Alkaline phosphatase, Glutamate dehydrogenase, Glutamate oxaloacetate transaminase and Glutamate pyruvate transaminase.
1(0,0,0,1) Details