Protein Information

Name ATPase is
Synonyms ATP11A; Cation transporting ATPase; ATPIH; ATPIS; ATPase Class VI type 11A; ATPase IS; ATPase class I type 11A; Phospholipid translocating ATPase…

Compound Information

Name parathion
CAS

Reference List

PubMed Abstract RScore(About this table)
2151019 Reddy MS, Rao KV: In vitro inhibition of Ca+2 ATPase by methylparathion in prawn: a kinetic approach. Biochem Int. 1990 Dec;22(6):1053-8.


The significant decrease in maximal velocity (Vmax) without appreciable change in apparent Michaelis-Menten constant (Km) suggests that the impact of methylparathion on Ca+2 ATPase is independent of substrate and is of a classical non-competitive type.
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11393797 Barber D, Hunt J, Ehrich M: Inhibition of calcium-stimulated ATPase in the hen brain P2 synaptosomal fraction by organophosphorus esters: relevance to delayed neuropathy. J Toxicol Environ Health A. 2001 May 25;63(2):101-13.


Following in vitro exposure to 10 (-3) to 10 (-5) M OP compounds, Ca-stimulated ATPase activity was inhibited by chlorpyrifos, chlorpyrifos-oxon, phenyl saligenin phosphate (PSP), and tri-o-tolyl phosphate (TOTP), but not by parathion, paraoxon, or diisopropyl fluorophosphate (DFP).
0(0,0,0,0) Details