Protein Information

Name ace 1
Synonyms ACE; ACE 1; ACE T; ACE1; Angiotensin I converting enzyme; Angiotensin I converting enzyme protein; CD143; CD143 antigen…

Compound Information

Name parathion
CAS

Reference List

PubMed Abstract RScore(About this table)
17017223 Cui F, Raymond M, Berthomieu A, Alout H, Weill M, Qiao CL: Recent emergence of insensitive acetylcholinesterase in Chinese populations of the mosquito Culex pipiens (Diptera: Culicidae). J Med Entomol. 2006 Sep;43(5):878-83.

According to previous findings, a unique mutation, G119S in the ace-1 gene, explained this high insensitivity.
Bioassays performed with a purified G119S strain indicated that this substitution was associated with high levels of resistance to chlorpyrifos, fenitrothion, malathion, and parathion, but low levels of resistance to dichlorvos, trichlorfon, and fenthion.
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