Protein Information

Name aspartate aminotransferase
Synonyms Aspartate Aminotransferase 1; GIG18; GOT 1; GOT1; Aspartate aminotransferase; Glutamate oxaloacetate transaminase 1; Transaminase A; Aspartate aminotransferases…

Compound Information

Name parathion
CAS

Reference List

PubMed Abstract RScore(About this table)
15889724 Icen E, Armutcu F, Buyukguzel K, Gurel A: Biochemical stress indicators of greater wax moth exposure to organophosphorus insecticides. J Econ Entomol. 2005 Apr;98(2):358-66.

We therefore investigated alterations in lipid peroxidation product, malondialdehyde (MDA) content, and alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities, in conjunction with AChE activity as biochemical stress indicators in greater wax moth, Galleria mellonella (L.) larvae for OPs methyl parathion (MP) and ethyl parathion (EP).
31(0,1,1,1) Details
17964717 Celik I, Suzek H: The hematological effects of methyl parathion in rats. J Hazard Mater. 2008 May 30;153(3):1117-21. Epub 2007 Sep 25.

The effects of methyl parathion (MP) at sublethal concentration on hematological constituent [red blood corpuscles (RBC), white blood corpuscles (WBC), mean cell volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), platelet (PLT) counts, hemoglobin (Hb) and hematocrite (HCT) levels] and serum damage marker enzymes [aspartate aminotransferase (AST), alanin aminotransferase (ALT), alkaline phosphatase (ALP) and lactate dehydrogenase (LDH)] of rats were investigated under laboratory conditions. 5 and 10 ppm dosages of MP were administered orally to six female rats ad libitum during the tests for 4 weeks consecutively.
6(0,0,1,1) Details
6229905 Prasada Rao KS, Ramana Rao KV: Tissue specific alteration of aminotransferases and total ATPases in the fish (Tilapia mossambica) under methyl parathion impact. Toxicol Lett. 1984 Jan;20(1):53-7.

The activity levels of aspartate aminotransferase (AAT), alanine aminotransferase (AlAT) and total adenosine triphosphatase (ATPase) were studied in muscle, gill, liver and brain tissues of control and methyl parathion exposed (MPE) fish.
6(0,0,1,1) Details
1907140 Reddy MS, Rao KV: Methylparathion, carbaryl and aldrin impact on nitrogen metabolism of prawn, Penaeus indicus. Biochem Int. 1991 Jan;23(2):389-96.


Increased alanine and aspartate aminotransferases demonstrates the onset of gluconeogenesis.
1(0,0,0,1) Details
15147928 de Aguiar LH, Moraes G, Avilez IM, Altran AE, Correa CF: Metabolical effects of Folidol 600 on the neotropical freshwater fish matrinxa, Brycon cephalus. Environ Res. 2004 Jun;95(2):224-30.

The neotropical freshwater fish matrinxa, Brycon cephalus (Gunther, 1869), was exposed to 1/3 of 96 h-LC50 of Folidol 600 (methyl parathion) for 96 h and allowed to recover for 24, 48, 96, and 192 h.
Acetylcholinesterase (AChE), alanine aminotransferase (ALAT), aspartate aminotransferase (AAT), lactate dehydrogenase (LDH), malate dehydrogenase (MDH), and glutamate dehydrogenase (GDH) were assayed in brain, liver, muscle, and plasma.
1(0,0,0,1) Details
17387711 Cui F, Tan Y, Qiao CL: Filariasis vector in China: insecticide resistance and population structure of mosquito Culex pipiens complex. Pest Manag Sci. 2007 May;63(5):453-8.

The resistance status of larvae to dichlorvos, parathion, chlorpyrifos, fenobucarb (BPMC) and propoxur were determined by bioassays, disclosing that they were more resistant to organophosphate (moderate or low resistance) than to carbamate (low or no significant resistance) insecticides.
Electrophoretic polymorphism at four putatively neutral loci (got-1, got-2, pgi and pgm) showed that the overall genetic differentiation found across all populations was significantly large (Fst = 0.28, P < 10 (-4)), and genetic exchange was slightly restricted by distance isolation (P = 0.018).
1(0,0,0,1) Details