| Name | Acetylcholinesterase |
|---|---|
| Synonyms | ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant… |
| Name | parathion-methyl |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16023954 | Chouteau C, Dzyadevych S, Durrieu C, Chovelon JM: A bi-enzymatic whole cell conductometric biosensor for heavy metal ions and pesticides detection in water samples. Biosens Bioelectron. 2005 Aug 15;21(2):273-81. Epub 2004 Dec 8. For pesticides, first experiments showed that paraoxon-methyl inhibits C. vulgaris AChE contrary to parathion-methyl and carbofuran. |
33(0,1,1,3) | Details |
| 1595894 | Kumaran S, Tran-Minh C: Determination of organophosphorous and insecticides by flow injection analysis. Anal Biochem. 1992 Jan;200(1):187-94. A flow injection system, incorporating an acetylcholinesterase (AChE) single bead string reactor (SBSR), for the determination of some organophosphorous (azinphos-ethyl, azinphos-methyl, bromophos-methyl, dichlorovos, fenitrothion, malathion, paraoxon, parathion-ethyl and parathion-methyl) and insecticides (carbofuran and carbaryl) is presented. |
6(0,0,1,1) | Details |
| 19130375 | Somerset V, Baker P, Iwuoha E: Mercaptobenzothiazole-on-gold organic phase biosensor systems: 1. J Environ Sci Health B. 2009 Feb;44(2):164-78. This paper reports the construction of the gold/mercaptobenzothiazole/polyaniline/acetylcholinesterase/polyvinylaceta te (Au/ MBT/PANI/AChE/PVAc) thick-film biosensor for the determination of certain organophosphate pesticide solutions in selected aqueous organic solvent solutions. The biosensor was then applied to detect a series of 5 organophosphorous pesticides in aqueous organic solvents and the pesticides studied were parathion-methyl, malathion and chlorpyrifos. |
4(0,0,0,4) | Details |
| 15508279 | Timur S, Telefoncu A: Acetylcholinesterase (AChE) electrodes based on gelatin and matrices for the pesticide detection. Artif Cells Blood Substit Immobil Biotechnol. 2004;32(3):427-42. Linear ranges for different organophosphates such as malathion, parathion-methyl, and methamidophos were detected by using both types of biosensor system. |
3(0,0,0,3) | Details |
| 19680907 | Chen C, Li Y, Chen M, Chen Z, Qian Y: Organophosphorus pesticide residues in milled rice (Oryza sativa) on the Chinese market and dietary risk assessment. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2009 Mar;26(3):340-7. The present study investigates the occurrence of acetylcholinesterase (AChE)-inhibiting organophosphorus (OP) pesticide residues in milled rice samples obtained form local markets in China during the period 2004-2006 and estimates their cumulative exposure. The results showed that 9.3% of the samples contained detectable residues of at least one of the seven target OP pesticides (chlorpyrifos, dichlorvos, omethoate, methamidophos, parathion-methyl, parathion and triazophos) mainly used for agriculture in China, with concentrations ranging 0.011-1.756 mg kg (-1). |
3(0,0,0,3) | Details |
| 11052723 | Gao JR, Zhu KY: Comparative toxicity of selected organophosphate insecticides against resistant and susceptible clones of the greenbug, Schizaphis graminum (Homoptera: aphididae). J Agric Food Chem. 2000 Oct;48(10):4717-22. The OR-1 clone showed lower levels of resistance to phenyl (parathion and parathion-methyl) and heterocyclic (chlorpyrifos) OPs than to aliphatic OPs (dimethoate, omethoate, disulfoton, and demeton-S-methyl), whereas the OR-2 clone showed a rather broad spectrum of resistance to nearly all OP insecticides examined. In vitro inhibition of acetylcholinesterase (AChE) using six selected OP oxon analogues showed that alterations of AChE were involved in resistance to all OP compounds examined in both the OR-1 and OR-2 clones. |
3(0,0,0,3) | Details |
| 11481665 | Abu-Qare AW, Abou-Donia MB: Inhibition and recovery of maternal and fetal cholinesterase enzyme activity following a single cutaneous dose of methyl parathion and diazinon, alone and in combination, in pregnant rats. J Appl Toxicol. 2001 Jul-Aug;21(4):307-16. Methyl parathion significantly inhibited maternal and fetal brain acetylcholinesterase (AChE) and plasma butyrylcholinesterase (BuChE) activity within 24 h after dosing. |
3(0,0,0,3) | Details |
| 17963125 | Gulalp B, Gokel Y, Gumurdulu D, Seydaoglu G, Daglioglu K, Dikmen N, Karcioglu O: The effect of parathion-methyl and antidotes on parotid and pancreatic glands: a pilot experimental study. Int J Toxicol. 2007 Sep-Oct;26(5):383-8. After the administration of the chemicals, blood samples were drawn to test for amylase, lipase, acetylcholinesterase (AChE), and butyrylcholinesterase (BChE), while pancreatic and parotid glands of each rat were removed for light microscopic examination. |
2(0,0,0,2) | Details |
| 16163484 | Suprun E, Evtugyn G, Budnikov H, Ricci F, Moscone D, Palleschi G: Acetylcholinesterase sensor based on screen-printed carbon electrode modified with prussian blue. Anal Bioanal Chem. 2005 Oct;383(4):597-604. Epub 2005 Oct 19. The ChE/PB sensor makes it possible to detect Aldicarb, Paraoxon and Parathion-Methyl with limits of detection 30, 10 and 5 ppb, respectively (incubation 10 min). |
2(0,0,0,2) | Details |
| 17824663 | Walz I, Schwack W: Cutinase inhibition by means of insecticidal organophosphates and carbamates. 3. J Agric Food Chem. 2007 Oct 3;55(20):8177-86. Epub 2007 Sep 8. Chloroperoxidase (CPO) from Caldariomyces fumago combined with peroxide and proved to be most efficient for the transformation of organophosphorothionate pesticides, i.e., chlorpyrifos, chlorpyrifos-methyl, parathion, and parathion-methyl, into their more potent serine esterase inhibiting oxon analogues. This type of enzymatic oxidation is easier to perform and more efficient, as compared to or N-bromosuccinimide, used for acetylcholine esterase (AChE) assay in water analyses, but is insufficient for complex matrices such as plant sample extracts. |
1(0,0,0,1) | Details |
| 19674799 | Tryfonos M, Papaefthimiou C, Antonopoulou E, Theophilidis G: Comparing the inhibitory effects of five protoxicant organophosphates (azinphos-methyl, parathion-methyl, chlorpyriphos-methyl, methamidophos and diazinon) on the spontaneously beating auricle of Sparus aurata: an in vitro study. Aquat Toxicol. 2009 Sep 14;94(3):211-8. Epub 2009 Jul 16. Organophosphates (OPs) can provoke toxicity by inhibiting acetylcholinesterase (AChE) in non-target organisms, like fish. |
1(0,0,0,1) | Details |
| 11750078 | Howard MD, Pope CN: In vitro effects of chlorpyrifos, parathion, methyl parathion and their oxons on cardiac muscarinic receptor binding in neonatal and adult rats. Toxicology. 2002 Jan 15;170(1-2):1-10. Organophosphorus insecticides elicit toxicity by inhibiting acetylcholinesterase. |
1(0,0,0,1) | Details |
| 15793557 | Isoda H, Talorete TP, Han J, Oka S, Abe Y, Inamori Y: Effects of organophosphorous pesticides used in china on various mammalian cells. Environ Sci. 2005;12(1):9-19. Five organophosphorous pesticides, monocrotophos, omethoate, parathion-methyl, phoxim and dichlorvos, were examined for their effects on mammalian cell lines to determine their potential impact on physiological functions in vivo. The different pesticides reduced the acetylcholinesterase (AChE) activity of the rat neuronal cell line PC12 in a dose-dependent manner up to 100 microM. |
1(0,0,0,1) | Details |