Protein Information

Name vitamin D binding protein
Synonyms DBP; GC; DBP/GC; GC globulin; Group specific component; VDB; VDBG; VDBP…

Compound Information

Name ergocalciferol
CAS

Reference List

PubMed Abstract RScore(About this table)
2004595 Dusso AS, Negrea L, Gunawardhana S, Lopez-Hilker S, Finch J, Mori T, Nishii Y, Slatopolsky E, Brown AJ: On the mechanisms for the selective action of vitamin D analogs. Endocrinology. 1991 Apr;128(4):1687-92.

Because the lower potency of ergocalciferol compared to cholecalciferol in preventing or curing rickets in chicks was associated with a lower affinity of the avian vitamin D binding protein (DBP) for vitamin D2, we tested five analogs with low calcemic activity including 22-oxa-1,25-(OH) 2D3 (OCT), MC903, 1,25-(OH) 2-16 ene-23-yne D3, 1,25-(OH) 2-26,27 dihomo-22-ene-D3, and 1,25-(OH) 2-24-trihomo-22-ene-D3 for their affinity for rat serum DBP.
81(1,1,1,1) Details
18406498 Mistretta VI, Delanaye P, Chapelle JP, Souberbielle JC, Cavalier E: [Vitamin D2 or vitamin D3?] . Rev Med Interne. 2008 Oct;29(10):815-20. Epub 2008 Apr 11.

It is available in two forms: vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol).
Vitamin D2 has shorter plasma half-life and a lower affinity for the vitamin D binding protein, the hepatic vitamin D hydroxylase and the vitamin D receptor.
1(0,0,0,1) Details
17023693 Houghton LA, Vieth R: The case against ergocalciferol (vitamin D2) as a vitamin supplement. Am J Clin Nutr. 2006 Oct;84(4):694-7.

0(0,0,0,0) Details