Protein Information

Name cyclooxygenase 2
Synonyms COX 2; COX2; PHS2; PGG/HS; Cyclooxygenase 2; Cyclooxygenase 2b; Cycloxygenase 2; PGH synthase 2…

Compound Information

Name azadirachtin
CAS

Reference List

PubMed Abstract RScore(About this table)
20018848 Thoh M, Kumar P, Nagarajaram HA, Manna SK: Azadirachtin interacts with the tumor necrosis factor (TNF) binding domain of its receptors and inhibits TNF-induced biological responses. J Biol Chem. 2010 Feb 19;285(8):5888-95. Epub 2009 Dec 14.

Azadirachtin blocks TNF-induced activation of nuclear factor kappaB (NF-kappaB) and also expression of NF-kappaB-dependent genes such as adhesion molecules and cyclooxygenase 2.
81(1,1,1,1) Details