| Name | calmodulin |
|---|---|
| Synonyms | CALM; CAM; CALM 1; CALM 2; CALM 3; CALM1; CALM2; CALM3… |
| Name | permethrin |
|---|---|
| CAS | (3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 2988554 | Rashatwar SS, Matsumura F: Interaction of DDT and pyrethroids with calmodulin and its significance in the expression of enzyme activities of phosphodiesterase. Biochem Pharmacol. 1985 May 15;34(10):1689-94. Permethrin was the most potent inhibitor affecting calmodulin and, to a lesser extent, phosphodiesterase. |
86(1,1,1,6) | Details |
| 20143453 | Harrill JA, Knapp GW, Crofton KM: Splice variant specific increase in Ca (2+)/calmodulin- dependent protein kinase 1-gamma mRNA expression in response to acute pyrethroid exposure. J Biochem Mol Toxicol. 2010 Feb 8. Previous work demonstrated increases in the expression of Ca (2+)/calmodulin-dependent protein kinase 1-gamma (Camk1g) mRNA following acute deltamethrin and permethrin exposure. |
32(0,1,1,2) | Details |
| 9714322 | Fakata KL, Swanson SA, Vorce RL, Stemmer PM: Pyrethroid insecticides as phosphatase inhibitors. . Biochem Pharmacol. 1998 Jun 15;55(12):2017-22. The type II pyrethroid insecticides cis-cypermethrin (c-Cyp), trans-cypermethrin, deltamethrin (Delt), and fenvalerate A alpha (Fen), as well as the type I pyrethroid insecticides cis- and trans-permethrin and S-bioallethrin, were unable to inhibit the phosphatase activity of purified calcineurin under conditions of maximal activation by Ca2+ and calmodulin. |
31(0,1,1,1) | Details |
| 2957417 | Sahib IK, Prasada Rao KS, Desaiah D: Pyrethroid inhibition of basal and calmodulin stimulated Ca2+ ATPase and adenylate cyclase in rat brain. J Appl Toxicol. 1987 Apr;7(2):75-80. Effects of two classes of pyrethroids, permethrin and resmethrin (type I), cypermethrin and deltamethrin (type II), on basal (calmodulin-deficient) and calmodulin stimulated activities of Ca2+ ATPase and adenylate cyclase from rat brain were studied in vitro. |
10(0,0,1,5) | Details |
| 1459649 | Yasmeen N, Nayeemunnisa: Insecticide induced disruptions in functioning of developing brain of Rana cyanophlictis. Indian J Exp Biol. 1992 Aug;30(8):701-4. Synthetic pyrethroid insecticide permethrin significantly decreased the levels of regulatory proteins (S-100 and calmodulin) in the developing CNS of tadpoles of R. cyanophlictis. |
6(0,0,1,1) | Details |
| 12785591 | Cassano G, Bellantuono V, Ardizzone C, Lippe C: Pyrethroid stimulation of ion transport across frog skin. . Environ Toxicol Chem. 2003 Jun;22(6):1330-4. The short-circuit current value (estimate of ion transport) was increased by each of the eight pyrethroids tested, with the following order of potency: lambda-cyhalothrin > deltamethrin > alpha-cypermethrin = beta-cyfluthrin > bioallethrin > permethrin > bioresmethrin > phenothrin. Finally, the stimulation by pyrethroids was inhibited by indomethacin and W7 (inhibitors of cyclooxygenases and the Ca2+/calmodulin system, respectively). |
1(0,0,0,1) | Details |