Protein Information

Name Fatty acid amide hydrolase
Synonyms Anandamide amidohydrolase; FAAH; Fatty acid amide hydrolase; Oleamide hydrolase; Oleamide hydrolase Anandamide amidohydrolase FAAH; Fatty acid amide hydrolases; Oleamide hydrolases; Oleamide hydrolase Anandamide amidohydrolase FAAHs

Compound Information

Name phenmedipham
CAS

Reference List

PubMed Abstract RScore(About this table)
19850474 Vincent F, Nguyen MT, Emerling DE, Kelly MG, Duncton MA: Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inhibitors. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6793-6. Epub 2009 Sep 30.

These studies revealed phenmedipham 13 and amperozide 14 to be inhibitors of human FAAH, with an IC (50) of 377 nM and 1.34 microM, respectively.
114(1,2,2,4) Details